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Open Access
Peer-reviewed
Research Article
Neuroprotective Effect of a New Synthetic Aspirin-decursinol Adduct in Experimental Animal Models of Ischemic Stroke
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Bing Chun Yan ,
Contributed equally to this work with: Bing Chun Yan, Joon Ha Park
Affiliation Institute of Integrative traditional & western Medicine,Medical College, Yangzhou University, Yangzhou, China
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Joon Ha Park ,
Contributed equally to this work with: Bing Chun Yan, Joon Ha Park
Affiliation Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon, South Korea
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Bich Na Shin,
Affiliation Department of Physiology, College of Medicine and Institute of Neurodegeneration and Neuroregeneration, Hallym University, Chuncheon, South Korea
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Ji Hyeon Ahn,
Affiliation Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon, South Korea
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In Hye Kim,
Affiliation Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon, South Korea
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Jae-Chul Lee,
Affiliation Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon, South Korea
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Ki-Yeon Yoo,
Affiliation Department of Oral Anatomy, College of Dentistry, Gangneung-Wonju National University, Gangneung, South Korea
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In Koo Hwang,
Affiliation Department of Anatomy and Cell Biology, College of Veterinary Medicine and Research Institute for Veterinary Science, Seoul National University, Seoul, South Korea
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Jung Hoon Choi,
Affiliation Department of Anatomy, College of Veterinary Medicine, Kangwon National University, Chuncheon, South Korea
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Jeong Ho Park,
Affiliation Division of Applied Chemistry and Biotechnology, Hanbat National University, Daejeon, South Korea
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Yun Lyul Lee,
Affiliation Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon, South Korea
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Hong-Won Suh,
Affiliation Department of Pharmacology and Institute of Natural Medicine, College of Medicine Hallym University, Chuncheon, South Korea
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Jong-Gab Jun,
Affiliation Department of Chemistry and Institute of Applied Chemistry, Hallym University, Chuncheon, South Korea
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Young-Guen Kwon,
Affiliation Department of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul, South Korea
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Young-Myeong Kim,
Affiliation Vascular System Research Center and Department of Molecular and Cellular Biochemistry, School of Medicine, Kangwon National University, Chuncheon, South Korea
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Seung-Hae Kwon,
Affiliation Division of Analytical Bio-imaging, Chuncheon Center, Korea Basic Science Institute, Chuncheon, Kangwon, South Korea
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Song Her,
Affiliation Division of Analytical Bio-imaging, Chuncheon Center, Korea Basic Science Institute, Chuncheon, Kangwon, South Korea
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Jin Su Kim,
Affiliation Molecular Imaging Research Center, Korea Institute of Radiological and Medical Sciences, Seoul, South Korea
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Byung-Hwa Hyun,
Affiliation Laboratory Animal Center, OSONG Medical Innovation Foundation, Osong, South Korea
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Chul-Kyu Kim,
Affiliation Laboratory Animal Center, OSONG Medical Innovation Foundation, Osong, South Korea
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Jun Hwi Cho,
Affiliation Department of Emergency Medicine and Institute of Medical Sciences, Kangwon National University Hospital, School of Medicine, Kangwon National University, Chuncheon, South Korea
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Choong Hyun Lee ,
* E-mail: mhwon@kangwon.ac.kr (MHW); anaphy@dankook.ac.kr (CHL)
Affiliation Department of Anatomy and Physiology, College of Pharmacy, Dankook University, Cheonan, South Korea
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Moo-Ho Won
* E-mail: mhwon@kangwon.ac.kr (MHW); anaphy@dankook.ac.kr (CHL)
Affiliation Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon, South Korea
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Neuroprotective Effect of a New Synthetic Aspirin-decursinol Adduct in Experimental Animal Models of Ischemic Stroke
- Bing Chun Yan,
- Joon Ha Park,
- Bich Na Shin,
- Ji Hyeon Ahn,
- In Hye Kim,
- Jae-Chul Lee,
- Ki-Yeon Yoo,
- In Koo Hwang,
- Jung Hoon Choi,
- Jeong Ho Park
- Published: September 20, 2013
- https://doi.org/10.1371/journal.pone.0074886