6-Shogaol Induces Apoptosis in Human Hepatocellular Carcinoma Cells and Exhibits Anti-Tumor Activity In Vivo through Endoplasmic Reticulum Stress

Rong Hu; Ping Zhou; Yong-Bo Peng; Xiaojun Xu; Jiang Ma; Qun Liu; Lei Zhang; Xiao-Dong Wen; Lian-Wen Qi; Ning Gao; Ping Li

doi:10.1371/journal.pone.0039664

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Open Access

Peer-reviewed

Research Article

6-Shogaol Induces Apoptosis in Human Hepatocellular Carcinoma Cells and Exhibits Anti-Tumor Activity In Vivo through Endoplasmic Reticulum Stress

Rong Hu ,

Contributed equally to this work with: Rong Hu, Ping Zhou

Affiliation State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, China
⨯
Ping Zhou ,

Contributed equally to this work with: Rong Hu, Ping Zhou

Affiliation State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, China
⨯
Yong-Bo Peng,

Affiliation State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, China
⨯
Xiaojun Xu,

Affiliation State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, China
⨯
Jiang Ma,

Affiliation State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, China
⨯
Qun Liu,

Affiliation State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, China
⨯
Lei Zhang,

Affiliation State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, China
⨯
Xiao-Dong Wen,

Affiliation State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, China
⨯
Lian-Wen Qi,

Affiliation State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, China
⨯
Ning Gao ,

* E-mail: gaoning59@yahoo.com.cn (NG); liping2004@126.com (PL)

Affiliation Department of Pharmacognosy, College of Pharmacy, 3rd Military Medical University, Chongqing, China
⨯
Ping Li

* E-mail: gaoning59@yahoo.com.cn (NG); liping2004@126.com (PL)

Affiliation State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, China
⨯

6-Shogaol Induces Apoptosis in Human Hepatocellular Carcinoma Cells and Exhibits Anti-Tumor Activity In Vivo through Endoplasmic Reticulum Stress

Rong Hu,
Ping Zhou,
Yong-Bo Peng,
Xiaojun Xu,
Jiang Ma,
Qun Liu,
Lei Zhang,
Xiao-Dong Wen,
Lian-Wen Qi,
Ning Gao

Published: June 29, 2012
https://doi.org/10.1371/journal.pone.0039664

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24 Sep 2016
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dose of shogaol Posted by shassan932 on 24 Sep 2016 at 12:00 GMT

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