About the Authors

Rolf A. Heckemann

rolf.heckemann@medtechwest.se

Affiliations MedTech West at Sahlgrenska University Hospital, Gothenburg, Sweden, Institute of Neuroscience and Physiology, Gothenburg University, Gothenburg, Sweden, Centre for Brain Sciences, Imperial College, London, United Kingdom, The Neurodis Foundation, Lyon, France

Christian Ledig

Affiliation Department of Computing, Imperial College, London, United Kingdom

Katherine R. Gray

Affiliation Department of Computing, Imperial College, London, United Kingdom

Paul Aljabar

Affiliations Department of Computing, Imperial College, London, United Kingdom, Imaging Sciences and Biomedical Engineering, King’s College, London, United Kingdom

Daniel Rueckert

Affiliation Department of Computing, Imperial College, London, United Kingdom

Joseph V. Hajnal

Affiliation Imaging Sciences and Biomedical Engineering, King’s College, London, United Kingdom

Alexander Hammers

Affiliations The Neurodis Foundation, Lyon, France, Imaging Sciences and Biomedical Engineering, King’s College, London, United Kingdom

Competing Interests

CL and KRG are employees of IXICO PLC., UK, a provider of medical image analysis services. DR and JVH are founders and scientific advisors of IXICO PLC. RAH, PA, and AH declare that they have no competing interests. This does not alter the authors' adherence to PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: RAH JVH DR AH PA. Performed the experiments: RAH CL KRG. Analyzed the data: RAH AH CL KRG. Contributed reagents/materials/analysis tools: RAH PA DR. Wrote the paper: RAH CL KRG PA DR JVH AH.