NF-κB Affects Proliferation and Invasiveness of Breast Cancer Cells by Regulating CD44 Expression

Shannon M. Smith; Yi Lisa Lyu; Li Cai

doi:10.1371/journal.pone.0106966

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Open Access

Peer-reviewed

Research Article

NF-κB Affects Proliferation and Invasiveness of Breast Cancer Cells by Regulating CD44 Expression

Shannon M. Smith,

Current address: The Children's Hospital of Philadelphia, Room 5024 CTRB, 3501 Civic Center, Boulevard, Philadelphia PA 19104, United States of America

Affiliation Cell and Developmental Biology Graduate Program, Rutgers University, Piscataway, New Jersey, United States of America
⨯
Yi Lisa Lyu,

Affiliation Department of Pharmacology, Robert Wood Johnson Medical School, Rutgers University, Piscataway, New Jersey, United States of America
⨯
Li Cai

* E-mail: lcai@rutgers.edu

Affiliations Cell and Developmental Biology Graduate Program, Rutgers University, Piscataway, New Jersey, United States of America, Department of Biomedical Engineering, Rutgers University, Piscataway, New Jersey, United States of America
⨯

NF-κB Affects Proliferation and Invasiveness of Breast Cancer Cells by Regulating CD44 Expression

Shannon M. Smith,
Yi Lisa Lyu,
Li Cai

Published: September 3, 2014
https://doi.org/10.1371/journal.pone.0106966

About the Authors

Shannon M. Smith

Current address: The Children's Hospital of Philadelphia, Room 5024 CTRB, 3501 Civic Center, Boulevard, Philadelphia PA 19104, United States of America

Affiliation Cell and Developmental Biology Graduate Program, Rutgers University, Piscataway, New Jersey, United States of America

Yi Lisa Lyu

Affiliation Department of Pharmacology, Robert Wood Johnson Medical School, Rutgers University, Piscataway, New Jersey, United States of America

Li Cai

* E-mail: lcai@rutgers.edu

Affiliations Cell and Developmental Biology Graduate Program, Rutgers University, Piscataway, New Jersey, United States of America, Department of Biomedical Engineering, Rutgers University, Piscataway, New Jersey, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: LC YLL. Performed the experiments: SMS. Analyzed the data: LC SMS YLL. Contributed reagents/materials/analysis tools: SMS LC. Contributed to the writing of the manuscript: SMS YLL LC.

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Transcription factors
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Cancer treatment
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Breast cancer
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Electrophoretic mobility shift assay
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Cell proliferation
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Cancer cell migration
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Cell binding
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Prostate cancer
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