About the Authors

Jun Li

Affiliation Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America

Liangcai Gu

Affiliation Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America

John Aach

Affiliation Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America

George M. Church

gchurch@genetics.med.harvard.edu

Affiliation Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America

Competing Interests

Merck KGaA provided funding for this study. None of the authors are employees of/affiliated with Merck KGaA. There are no patents, products in development or marketed products to declare. This does not alter the authors' adherence to all PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: JL GMC. Performed the experiments: JL LG. Analyzed the data: JL. Contributed reagents/materials/analysis tools: JL LG. Contributed to the writing of the manuscript: JL LG JA GMC.