About the Authors

Hiroshi Kataoka

Contributed equally to this work with: Hiroshi Kataoka, Hajime Kono

Affiliation Department of Pathology, UMass Medical School, Worcester, Massachusetts, United States of America

Hajime Kono

Contributed equally to this work with: Hiroshi Kataoka, Hajime Kono

Affiliation Department of Internal Medicine, Teikyo University School of Medicine, Tokyo, Japan

Zubin Patel

Affiliation Department of Pathology, UMass Medical School, Worcester, Massachusetts, United States of America

Kenneth L. Rock

Kenneth.rock@umassmed.edu

Affiliation Department of Pathology, UMass Medical School, Worcester, Massachusetts, United States of America

Competing Interests

Bristol-Myers Squibb provided funding towards this study. There are no patents, products in development or marketed products to declare. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: H. Kataoka H. Kono KLR. Performed the experiments: H. Kataoka H. Kono ZP. Analyzed the data: H. Kataoka H. Kono ZP KLR. Contributed reagents/materials/analysis tools: H. Kataoka H. Kono ZP KLR. Wrote the paper: H. Kataoka H. Kono KLR.