Nesfatin-1 Influences the Excitability of Glucosensing Neurons in the Dorsal Vagal Complex and Inhibits Food Intake

Jing Dong; Hong-Zai Guan; Zheng-Yao Jiang; Xi Chen

doi:10.1371/journal.pone.0098967

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Open Access

Peer-reviewed

Research Article

Nesfatin-1 Influences the Excitability of Glucosensing Neurons in the Dorsal Vagal Complex and Inhibits Food Intake

Jing Dong ,

Contributed equally to this work with: Jing Dong, Hong-Zai Guan

Affiliations Department of Special Medicine, Medical College of Qingdao University, Qingdao, China, Department of Physiology, Medical College of Qingdao University, Qingdao, China
⨯
Hong-Zai Guan ,

Contributed equally to this work with: Jing Dong, Hong-Zai Guan

Affiliation Department of Physiology, Medical College of Qingdao University, Qingdao, China
⨯
Zheng-Yao Jiang ,

* E-mail: qd-zyj@163.com (ZYJ); casey1201@163.com (XC)

Affiliation Department of Physiology, Medical College of Qingdao University, Qingdao, China
⨯
Xi Chen

* E-mail: qd-zyj@163.com (ZYJ); casey1201@163.com (XC)

Affiliation Department of Physiology, Medical College of Qingdao University, Qingdao, China
⨯

Nesfatin-1 Influences the Excitability of Glucosensing Neurons in the Dorsal Vagal Complex and Inhibits Food Intake

Jing Dong,
Hong-Zai Guan,
Zheng-Yao Jiang,
Xi Chen

Published: June 6, 2014
https://doi.org/10.1371/journal.pone.0098967

About the Authors

Jing Dong

Contributed equally to this work with: Jing Dong, Hong-Zai Guan

Affiliations Department of Special Medicine, Medical College of Qingdao University, Qingdao, China, Department of Physiology, Medical College of Qingdao University, Qingdao, China

Hong-Zai Guan

Contributed equally to this work with: Jing Dong, Hong-Zai Guan

Affiliation Department of Physiology, Medical College of Qingdao University, Qingdao, China

Zheng-Yao Jiang

* E-mail: qd-zyj@163.com (ZYJ); casey1201@163.com (XC)

Affiliation Department of Physiology, Medical College of Qingdao University, Qingdao, China

Xi Chen

* E-mail: qd-zyj@163.com (ZYJ); casey1201@163.com (XC)

Affiliation Department of Physiology, Medical College of Qingdao University, Qingdao, China

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: XC ZYJ. Performed the experiments: JD HZG. Analyzed the data: XC. Wrote the paper: ZYJ XC.

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Neurons
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Food
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Glucose
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Weight gain
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Depression
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Hindbrain
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Action potentials
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Electrophysiology
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