About the Authors

Priscila Portugal dos Santos

Affiliation Department of Internal Medicine, Botucatu Medical School, UNESP - Universidade Estadual Paulista, Botucatu, São Paulo, Brazil

Bruna Paola Murino Rafacho

Affiliation Department of Internal Medicine, Botucatu Medical School, UNESP - Universidade Estadual Paulista, Botucatu, São Paulo, Brazil

Andréa de Freitas Gonçalves

Affiliation Department of Internal Medicine, Botucatu Medical School, UNESP - Universidade Estadual Paulista, Botucatu, São Paulo, Brazil

Rodrigo Gibin Jaldin

Affiliation Department of Surgery and Orthopaedics, Botucatu Medical School, UNESP - Universidade Estadual Paulista, Botucatu, São Paulo, Brazil

Thiago Bruder do Nascimento

Affiliation Department of Pharmacology, School of Medicine at Ribeirao Preto - USP, University of São Paulo, São Paulo, Brazil

Marcondes Alves Barbosa Silva

Affiliation Department of Pharmacology, School of Medicine at Ribeirao Preto - USP, University of São Paulo, São Paulo, Brazil

Stêfany Bruno Assis Cau

Affiliation Department of Pharmacology, School of Medicine at Ribeirao Preto - USP, University of São Paulo, São Paulo, Brazil

Meliza Goi Roscani

Affiliation Department of Internal Medicine, Botucatu Medical School, UNESP - Universidade Estadual Paulista, Botucatu, São Paulo, Brazil

Paula Schimdt Azevedo

Affiliation Department of Internal Medicine, Botucatu Medical School, UNESP - Universidade Estadual Paulista, Botucatu, São Paulo, Brazil

Marcos Ferreira Minicucci

Affiliation Department of Internal Medicine, Botucatu Medical School, UNESP - Universidade Estadual Paulista, Botucatu, São Paulo, Brazil

Rita de Cássia Tostes

Affiliation Department of Pharmacology, School of Medicine at Ribeirao Preto - USP, University of São Paulo, São Paulo, Brazil

Leonardo Antonio Memede Zornoff

Affiliation Department of Internal Medicine, Botucatu Medical School, UNESP - Universidade Estadual Paulista, Botucatu, São Paulo, Brazil

Sergio Alberto Rupp de Paiva

paiva@fmb.unesp.br

Affiliation Department of Internal Medicine, Botucatu Medical School, UNESP - Universidade Estadual Paulista, Botucatu, São Paulo, Brazil

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: PPS PSA MFM LAMZ SARP. Performed the experiments: PPS BPMR AFG RGJ TBN MABS SBAC MGR. Analyzed the data: PPS RGJ TBN RCT LAMZ SARP. Contributed reagents/materials/analysis tools: PPS PSA MFM RCT LAMZ SARP. Wrote the paper: PPS RCT SARP.