About the Authors

Bettina Mavrommatis

Current address: Division of Immunoregulation, MRC National Institute for Medical Research, London, United Kingdom

Affiliation The Royal Veterinary College, Hatfield, United Kingdom

Victoria Offord

Affiliation The Royal Veterinary College, Hatfield, United Kingdom

Robert Patterson

Affiliation The Royal Veterinary College, Hatfield, United Kingdom

Mick Watson

Affiliation ARK-Genomics, The Roslin Institute & R(D)SVS, University of Edinburgh, Midlothian, Edinburgh, United Kingdom

Theo Kanellos

Affiliation Zoetis Animal Health, Paris, France

Falko Steinbach

Affiliation Department of Virology, Animal Health and Veterinary Laboratories Agency, Addlestone, United Kingdom

Sylvia Grierson

Affiliation Department of Virology, Animal Health and Veterinary Laboratories Agency, Addlestone, United Kingdom

Dirk Werling

Dwerling@RVC.AC.UK

Affiliation The Royal Veterinary College, Hatfield, United Kingdom

Competing Interests

Theo Kanellos is an employee of Zoetis Animal Health, Paris, whose company provided funding towards this study. Biobest Laboratories also provided funding for this study. There are no patents, products in development or marketed products to declare. This does not alter our adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: BM FS SG DW. Performed the experiments: BM RP. Analyzed the data: BM VO MW DW. Contributed reagents/materials/analysis tools: FS TK. Wrote the paper: BM RP DW. Scientific discussion: TK.