About the Authors

Linda Nguyen

Affiliation Department of Basic Pharmaceutical Sciences, and Department of Behavioral Medicine and Psychiatry, West Virginia University, Morgantown, West Virginia, United States of America

Matthew J. Robson

Current address: Department of Pharmacology, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America

Affiliation Department of Basic Pharmaceutical Sciences, and Department of Behavioral Medicine and Psychiatry, West Virginia University, Morgantown, West Virginia, United States of America

Jason R. Healy

Affiliation Department of Basic Pharmaceutical Sciences, and Department of Behavioral Medicine and Psychiatry, West Virginia University, Morgantown, West Virginia, United States of America

Anna L. Scandinaro

Affiliation Department of Basic Pharmaceutical Sciences, and Department of Behavioral Medicine and Psychiatry, West Virginia University, Morgantown, West Virginia, United States of America

Rae R. Matsumoto

rmatsumoto@hsc.wvu.edu

Affiliation Department of Basic Pharmaceutical Sciences, and Department of Behavioral Medicine and Psychiatry, West Virginia University, Morgantown, West Virginia, United States of America

Competing Interests

Dr. Matsumoto reports having received consultant fees and research funding from Avanir Pharmaceuticals, Inc. This does not alter the authors' adherence to PLOS ONE policies on sharing data and materials. The other authors report no financial or conflicts of interest.

Author Contributions

Conceived and designed the experiments: LN MJR RRM. Performed the experiments: LN MJR JRH ALS. Analyzed the data: LN MJR JRH ALS RRM. Wrote the paper: LN RRM. Edited the manuscript: LN MJR JRH ALS RRM.