About the Authors

Gianfranco Spalletta

g.spalletta@hsantalucia.it

Affiliation Neuropsychiatry Laboratory, Department of Clinical and Behavioral Neurology, IRCCS Santa Lucia Foundation, Rome, Italy

Carlo Caltagirone

Affiliations Neuropsychiatry Laboratory, Department of Clinical and Behavioral Neurology, IRCCS Santa Lucia Foundation, Rome, Italy, Department of System Medicine, University of Rome “Tor Vergata”, Rome, Italy

Alessandro Padovani

Affiliation Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy

Sandro Sorbi

Affiliation Department of Neurological and Psychiatric Sciences, University of Florence, Florence, Italy

Mahmood Attar

Affiliation Novartis Farma Italia, Origgio (Varese), Italy

Delia Colombo

Affiliation Novartis Farma Italia, Origgio (Varese), Italy

Luca Cravello

Affiliation Neuropsychiatry Laboratory, Department of Clinical and Behavioral Neurology, IRCCS Santa Lucia Foundation, Rome, Italy

on behalf of the E V O L U T I O N study Working Group

Membership of the EVOLUTION study Working Group is provided in the Acknowledgments.

Competing Interests

Mahmood Attar and Delia Colombo are members of the Medical department of the Novartis Farma SpA Italia. Gianfranco Spalletta was funded from Novartis Farma SpA Italia for consultancy. Carlo Caltagirone, Alessandro Padovani and Sandro Sorbi were funded from Novartis Farma SpA Italia for editorial board and consultancy. Luca Cravello has no competing interest. The authors confirm that this does not alter their adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: GS CC AP SS MA DC. Performed the experiments: GS CC AP SS LC. Analyzed the data: GS MA LC. Contributed reagents/materials/analysis tools: GS CC AP SS MA. Wrote the paper: GS LC.