About the Authors

Chong Wang

Affiliation Department of Neurology, Qingdao Municipal Hospital, School of Medicine, Qingdao University, Qingdao, Shandong, China

Jin-Tai Yu

dr.tanlan@163.com (LT); yu-jintai@163.com (JTY)

Affiliations Department of Neurology, Qingdao Municipal Hospital, School of Medicine, Qingdao University, Qingdao, Shandong, China, Department of Neurology, Qingdao Municipal Hospital, Nanjing Medical University, Nanjing, Jiangsu, China, College of Medicine and Pharmaceutics, Ocean University of China, Qingdao, Shandong, China

Hui-Fu Wang

Affiliation Department of Neurology, Qingdao Municipal Hospital, Nanjing Medical University, Nanjing, Jiangsu, China

Teng Jiang

Affiliation Department of Neurology, Qingdao Municipal Hospital, Nanjing Medical University, Nanjing, Jiangsu, China

Chen-Chen Tan

Affiliation Department of Neurology, Qingdao Municipal Hospital, School of Medicine, Qingdao University, Qingdao, Shandong, China

Xiang-Fei Meng

Affiliation Department of Neurology, Qingdao Municipal Hospital, School of Medicine, Qingdao University, Qingdao, Shandong, China

Holly D. Soares

Affiliation Bristol-Myers Squibb, Wallingford Center, Connecticut, United States of America

Lan Tan

dr.tanlan@163.com (LT); yu-jintai@163.com (JTY)

Affiliations Department of Neurology, Qingdao Municipal Hospital, School of Medicine, Qingdao University, Qingdao, Shandong, China, Department of Neurology, Qingdao Municipal Hospital, Nanjing Medical University, Nanjing, Jiangsu, China, College of Medicine and Pharmaceutics, Ocean University of China, Qingdao, Shandong, China

Competing Interests

One co-author Holly D. Soares,is employed by a commercial company (Bristol-Myers Squibb). This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: LT J-TY. Performed the experiments: CW H-FW J-TY. Analyzed the data: C-CT X-FM HS. Contributed reagents/materials/analysis tools: TJ. Wrote the paper: CW J-TY.