About the Authors

Toshiyuki Kawai

kawait@kuhp.kyoto-u.ac.jp

Affiliation Department of Orthopedic Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan

Mitsuru Takemoto

Affiliation Department of Orthopedic Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan

Shunsuke Fujibayashi

Affiliation Department of Orthopedic Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan

Haruhiko Akiyama

Affiliation Department of Orthopedic Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan

Masashi Tanaka

Affiliation Department of Orthopedic Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan

Seiji Yamaguchi

Affiliation Department of Biomedical Sciences, College of Life and Health Sciences, Chubu University, Kasugai, Aichi, Japan

Deepak K. Pattanayak

Affiliation Department of Biomedical Sciences, College of Life and Health Sciences, Chubu University, Kasugai, Aichi, Japan

Kenji Doi

Affiliation Osaka Yakin Kogyo Co., ltd., Osaka, Japan

Tomiharu Matsushita

Affiliation Department of Biomedical Sciences, College of Life and Health Sciences, Chubu University, Kasugai, Aichi, Japan

Takashi Nakamura

Affiliation National Hospital Organization Kyoto Medical Center, Kyoto, Japan

Tadashi Kokubo

Affiliation Department of Biomedical Sciences, College of Life and Health Sciences, Chubu University, Kasugai, Aichi, Japan

Shuichi Matsuda

Affiliation Department of Orthopedic Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan

Competing Interests

Kenji Doi is employed by Osaka Yakin Kogyo Co., ltd. This does not alter the authors’ adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: T. Kawai T. Kokubo TN M. Takemoto SF. Performed the experiments: T. Kawai M. Tanaka DKP. Analyzed the data: T. Kawai T. Kokubo SY. Contributed reagents/materials/analysis tools: KD TM HA SM. Wrote the paper: T. Kawai.