About the Authors

Jia Gao

Affiliation Hefei National Laboratory for Physical Sciences at the Microscale, School of Life Science, University of Science and Technology of China, Hefei, Anhui, China

Rongsheng Ma

Affiliation Hefei National Laboratory for Physical Sciences at the Microscale, School of Life Science, University of Science and Technology of China, Hefei, Anhui, China

Wei Wang

Affiliation Pfizer Worldwide Research and Development, San Diego, California, United States of America

Na Wang

Affiliation Hefei National Laboratory for Physical Sciences at the Microscale, School of Life Science, University of Science and Technology of China, Hefei, Anhui, China

Ryan Sasaki

Affiliation Advanced Chemistry Development Inc., Toronto, Ontario, Canada

David Snyderman

Affiliation Advanced Chemistry Development Inc., Toronto, Ontario, Canada

Jihui Wu

Affiliation Hefei National Laboratory for Physical Sciences at the Microscale, School of Life Science, University of Science and Technology of China, Hefei, Anhui, China

Ke Ruan

kruan@ustc.edu.cn

Affiliation Hefei National Laboratory for Physical Sciences at the Microscale, School of Life Science, University of Science and Technology of China, Hefei, Anhui, China

Competing Interests

The authors have the following interests. Dr. Wei Wang is employed by Pfizer Inc., Dr. Ryan Sasaki and David Snyderman are employed by Advanced Chemistry Development Inc. There are no patents, products in development or marketed products to declare. This does not alter the authors’ adherence to all the PLOS ONE policies on sharing data and materials, as detailed online in the guide for authors.

Author Contributions

Conceived and designed the experiments: JG KR. Performed the experiments: JG RSM NW DS. Analyzed the data: JG WW KR. Contributed reagents/materials/analysis tools: WW RS JW. Wrote the paper: JG KR.