About the Authors

Gamze Kilic

Affiliation Department of Medicine, Division of Endocrinology, Metabolism and Molecular Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States of America

Ana I. Alvarez-Mercado

Affiliation Department of Medicine, Division of Endocrinology and Metabolism, Tulane University Health Sciences Center, School of Medicine, New Orleans, LA, United States of America

Bader Zarrouki

Affiliation Montreal Diabetes Research Center, CRCHUM and Department of Medicine, University of Montréal, Montréal, QC, Canada

Darren Opland

Affiliation Division of Metabolism, Endocrinology and Diabetes, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, United States of America

Chong Wee Liew

Affiliation Section of Islet Cell Biology and Regenerative Medicine, Joslin Diabetes Center and Harvard Medical School, Boston, Massachusetts, United States of America

Laura C. Alonso

Affiliation Department of Medicine, Division of Diabetes, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America

Martin G. Myers Jr

Affiliation Division of Metabolism, Endocrinology and Diabetes, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, United States of America

Jean-Christophe Jonas

Affiliation Pole of Endocrinology, Diabetes and Nutrition, Institute of Clinical and Experimental Research, Catholic University of Louvain, Brussels, Belgium

Vincent Poitout

Affiliation Montreal Diabetes Research Center, CRCHUM and Department of Medicine, University of Montréal, Montréal, QC, Canada

Rohit N. Kulkarni

Affiliation Section of Islet Cell Biology and Regenerative Medicine, Joslin Diabetes Center and Harvard Medical School, Boston, Massachusetts, United States of America

Franck Mauvais-Jarvis

fmauvais@tulane.edu

Affiliations Department of Medicine, Division of Endocrinology, Metabolism and Molecular Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States of America, Department of Medicine, Division of Endocrinology and Metabolism, Tulane University Health Sciences Center, School of Medicine, New Orleans, LA, United States of America

Competing Interests

Franck Mauvais-Jarvis received research support from Pfizer Inc. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: GK FMJ. Performed the experiments: GK BZ CWL DO. Analyzed the data: GK AAM MGM JCJ RNK LCA FMJ. Contributed reagents/materials/analysis tools: LCA JCJ MGM VP RNK FMJ. Wrote the paper: GK AAM FMJ.