About the Authors
- Xuemei Zhang
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Affiliation Department of Bioengineering, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
- Allison L. Zajac
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Affiliation Cell Biology and Physiology, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
- Lingyan Huang
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Affiliation Integrated DNA Technologies, Inc., Coralville, Iowa, United States of America
- Mark A. Behlke
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Affiliation Integrated DNA Technologies, Inc., Coralville, Iowa, United States of America
- Andrew Tsourkas
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* E-mail: atsourk@seas.upenn.edu
Affiliation Department of Bioengineering, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
Competing Interests
The authors have the following interests. Dr. Mark Behlke and Dr. Ling Huang are employed by Integrated DNA Technologies, Inc. (IDT). IDT offers oligonucleotides for sale similar to some of the compounds described in the manuscript. IDT is, however, not a publicly traded company and they personally do not own any shares/equity in IDT. Dr. Andrew Tsourkas is an inventor on a pending patent application on ratiometric bimolecular beacons. There are no further patents, products in development or marketed products to declare. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials, as detailed online in the guide for authors. The information for the pending patent application is: Novel Molecular Beacons, 2009 Andrew Tsourkas and Antony Chen US Application Number: 61/243,586.
Author Contributions
Conceived and designed the experiments: AT XZ. Performed the experiments: XZ. Analyzed the data: ALZ. Contributed reagents/materials/analysis tools: LH MAB AT. Wrote the paper: XZ ALZ LH MAB AT.