About the Authors

Andreia Madeira

Affiliation Institute for Biotechnology and Bioengineering, Centre for Biological and Chemical Engineering, Department of Bioengineering, Instituto Superior Técnico, Universidade de Lisboa, Lisbon, Portugal

Sandra C. dos Santos

Affiliation Institute for Biotechnology and Bioengineering, Centre for Biological and Chemical Engineering, Department of Bioengineering, Instituto Superior Técnico, Universidade de Lisboa, Lisbon, Portugal

Pedro M. Santos

Current address: CBMA-Centre of Molecular and Environmental Biology, Department of Biology, University of Minho, Campus de Gualtar, Braga, Portugal

Affiliation Institute for Biotechnology and Bioengineering, Centre for Biological and Chemical Engineering, Department of Bioengineering, Instituto Superior Técnico, Universidade de Lisboa, Lisbon, Portugal

Carla P. Coutinho

Affiliation Institute for Biotechnology and Bioengineering, Centre for Biological and Chemical Engineering, Department of Bioengineering, Instituto Superior Técnico, Universidade de Lisboa, Lisbon, Portugal

Jean Tyrrell

Affiliation Centre of Microbial Host Interactions, Department of Science, ITT-Dublin, Dublin, Ireland

Siobhán McClean

Affiliation Centre of Microbial Host Interactions, Department of Science, ITT-Dublin, Dublin, Ireland

Máire Callaghan

Affiliation Centre of Microbial Host Interactions, Department of Science, ITT-Dublin, Dublin, Ireland

Isabel Sá-Correia

isacorreia@tecnico.ulisboa.pt

Affiliation Institute for Biotechnology and Bioengineering, Centre for Biological and Chemical Engineering, Department of Bioengineering, Instituto Superior Técnico, Universidade de Lisboa, Lisbon, Portugal

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: ISC MC PMS. Performed the experiments: PMS AM JT CPC. Analyzed the data: ISC AM SCS MC SM. Contributed reagents/materials/analysis tools: ISC MC SM. Wrote the manuscript: ISC AM SCS MC SM. 2-D DIGE-based proteomic analysis: PMS AM. Virulence and CAS assays: JT. qRT-PCR: CPC.