Partitioning the Human Transcriptome Using HKera, a Novel Classifier of Housekeeping and Tissue-Specific Genes

Austin W. T. Chiang; Grace T. W. Shaw; Ming-Jing Hwang

doi:10.1371/journal.pone.0083040

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Open Access

Peer-reviewed

Research Article

Partitioning the Human Transcriptome Using HKera, a Novel Classifier of Housekeeping and Tissue-Specific Genes

Austin W. T. Chiang ,

Contributed equally to this work with: Austin W. T. Chiang, Grace T. W. Shaw

Affiliations Bioinformatics Program, Taiwan International Graduate Program, Institute of Information Science, Academia Sinica, Taipei, Taiwan, Institute of BioMedical Informatics, NationalYang-MingUniversity, Taipei, Taiwan, Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan
⨯
Grace T. W. Shaw ,

Contributed equally to this work with: Austin W. T. Chiang, Grace T. W. Shaw

Affiliations Institute of BioMedical Informatics, NationalYang-MingUniversity, Taipei, Taiwan, Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan
⨯
Ming-Jing Hwang

* E-mail: mjhwang@ibms.sinica.edu.tw

Affiliations Bioinformatics Program, Taiwan International Graduate Program, Institute of Information Science, Academia Sinica, Taipei, Taiwan, Institute of BioMedical Informatics, NationalYang-MingUniversity, Taipei, Taiwan, Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan
⨯

Partitioning the Human Transcriptome Using HKera, a Novel Classifier of Housekeeping and Tissue-Specific Genes

Austin W. T. Chiang,
Grace T. W. Shaw,
Ming-Jing Hwang

Published: December 20, 2013
https://doi.org/10.1371/journal.pone.0083040

About the Authors

Austin W. T. Chiang

Contributed equally to this work with: Austin W. T. Chiang, Grace T. W. Shaw

Affiliations Bioinformatics Program, Taiwan International Graduate Program, Institute of Information Science, Academia Sinica, Taipei, Taiwan, Institute of BioMedical Informatics, NationalYang-MingUniversity, Taipei, Taiwan, Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan

Grace T. W. Shaw

Contributed equally to this work with: Austin W. T. Chiang, Grace T. W. Shaw

Affiliations Institute of BioMedical Informatics, NationalYang-MingUniversity, Taipei, Taiwan, Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan

Ming-Jing Hwang

* E-mail: mjhwang@ibms.sinica.edu.tw

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: AWTC GTWS MJH. Performed the experiments: AWTC GTWS. Analyzed the data: AWTC GTWS MJH. Wrote the paper: AWTC GTWS MJH.

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Gene expression
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Gene prediction
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Transcriptome analysis
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Machine learning algorithms
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Decision tree learning
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Microarrays
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Fourier analysis
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Machine learning
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