About the Authors

Bora Inceoglu

Affiliation Department of Entomology and UC Davis Comprehensive Cancer Center, University of California Davis, Sacramento, California, United States of America

Dorota Zolkowska

Affiliation Department of Neurology, School of Medicine, University of California Davis, Sacramento, California, United States of America

Hyun Ju Yoo

Affiliation Metabolomics Core Laboratory, Biomedical Research Center, Asan Institute of Life Sciences, Seoul, Korea

Karen M. Wagner

Affiliation Department of Entomology and UC Davis Comprehensive Cancer Center, University of California Davis, Sacramento, California, United States of America

Jun Yang

Affiliation Department of Entomology and UC Davis Comprehensive Cancer Center, University of California Davis, Sacramento, California, United States of America

Edward Hackett

Affiliation Department of Entomology and UC Davis Comprehensive Cancer Center, University of California Davis, Sacramento, California, United States of America

Sung Hee Hwang

Affiliation Department of Entomology and UC Davis Comprehensive Cancer Center, University of California Davis, Sacramento, California, United States of America

Kin Sing Stephen Lee

Affiliation Department of Entomology and UC Davis Comprehensive Cancer Center, University of California Davis, Sacramento, California, United States of America

Michael A. Rogawski

Affiliation Department of Neurology, School of Medicine, University of California Davis, Sacramento, California, United States of America

Christophe Morisseau

Affiliation Department of Entomology and UC Davis Comprehensive Cancer Center, University of California Davis, Sacramento, California, United States of America

Bruce D. Hammock

bdhammock@ucdavis.edu

Affiliation Department of Entomology and UC Davis Comprehensive Cancer Center, University of California Davis, Sacramento, California, United States of America

Competing Interests

Authors B.I., K.M.W., S.H.H., K.S.S.L, C.M. and B.D.H. are co-inventors on patents related to sEHI and pain by the University of California. The numbers and titles of the patents are available on request. These applications are not fully pertinent to the submitted manuscript. Per policy, these patents are owned and maintained institutionally by the University of California. B.D.H. has more than 100 patents and pending patent applications on various aspects of his research. This extensive list of patents and applications is publicly available at the USPTO website. There are no further patents, products in development or marketed products to declare. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: BI DZ MR BDH. Performed the experiments: BI DZ HJY KMW JY EH SHH KSSL CM. Analyzed the data: BI HJY JY DZ MR BDH. Contributed reagents/materials/analysis tools: DZ SHH KSSL CM JY. Wrote the paper: BI DZ BDH.