About the Authors

Andrea A. Jones

Affiliation Department of Psychiatry, University of British Columbia, Vancouver, Canada

Fidel Vila-Rodriguez

Affiliation Department of Psychiatry, University of British Columbia, Vancouver, Canada

William J. Panenka

Affiliation Department of Psychiatry, University of British Columbia, Vancouver, Canada

Olga Leonova

Affiliation Department of Psychiatry, University of British Columbia, Vancouver, Canada

Verena Strehlau

Affiliation Department of Psychiatry, University of British Columbia, Vancouver, Canada

Donna J. Lang

Affiliation Department of Radiology, University of British Columbia, Vancouver, Canada

Allen E. Thornton

Affiliation Department of Psychology, Simon Fraser University, Burnaby, Canada

Hubert Wong

Affiliation School of Population and Public Health, University of British Columbia, Vancouver, Canada

Alasdair M. Barr

Affiliation Department of Anesthesia, Pharmacology and Therapeutics, University of British Columbia, Vancouver, Canada

Ric M. Procyshyn

Affiliation Department of Psychiatry, University of British Columbia, Vancouver, Canada

Geoffrey N. Smith

Affiliation Department of Psychiatry, University of British Columbia, Vancouver, Canada

Tari Buchanan

Affiliation Department of Psychiatry, University of British Columbia, Vancouver, Canada

Mel Krajden

Affiliation Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, Canada

Michael Krausz

Affiliation Department of Psychiatry, University of British Columbia, Vancouver, Canada

Julio S. Montaner

Affiliation Department of Medicine, University of British Columbia, Vancouver, Canada

G. William MacEwan

Affiliation Department of Psychiatry, University of British Columbia, Vancouver, Canada

David J. Nutt

Affiliation Centre for Neuropsychopharmacology and Molecular Imaging, Division of Brain Sciences, Imperial College London, London, United Kingdom

William G. Honer

Affiliation Department of Psychiatry, University of British Columbia, Vancouver, Canada

Competing Interests

I have read the journal's policy and have the following competing interests: Dr. Honer has received consulting fees or sat on paid advisory boards for: MDH Consulting, In Silico, Novartis, Lundbeck and Roche. Dr. Barr has received consulting fees or sat on paid advisory boards for: Roche, Eli Lilly and Bristol-Myers Squibb. Dr. Procyshyn is a paid consultant for and has received speaker fees from AstraZeneca, Bristol-Myers Squibb, Janssen, Otsuka, Pfizer, and Sunovion. Dr. Krajden has received research grants form Merck Canada, Roche, Siemens and Gen-Probe but does not accept gifts, honoraria, or serve on advisory boards. Dr. Montaner has received grants from Abbott, Biolytical, Boehringer-Ingelheim, Bristol-Myers Squibb, Gilead Sciences, Janssen, Merck and ViiV Healthcare. Dr. MacEwan has received consulting fees or sat on paid advisory boards for: Apotex, AstraZeneca, BMS, Janssen, Lundbeck, Otsuka, Pfizer and Sunovion. He also received fees lectures sponsored by AstraZeneca, BMS, Janssen, Otsuka and Eli Lilly, and has received grants from Janssen Pharmaceuticals. Dr. Nutt is an advisor to Lundbeck and Novartis, and received speaking honoraria from BMS/Otsuka, Servier, Janssen and GSK. This does not alter our adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: DJL AET AMB RMP GNS TB M. Krausz JSM GWM WGH. Performed the experiments: AAJ FVR WJP OL VS DJL AET TB M. Krajden JSM GWM WGH. Analyzed the data: AAJ AET HW WGH. Contributed reagents/materials/analysis tools: DJN. Wrote the manuscript: AAJ FVR WJP OL VS DJL AET HW AMB RMP GNS TB M. Krausz M. Krajden JSM GWM WGH.