About the Authors

Ronald van ‘t Klooster

Affiliation Division of Image Processing, Department of Radiology, Leiden University Medical Center, Leiden, The Netherlands

Andrew J. Patterson

Affiliation University Department of Radiology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom

Victoria E. Young

Affiliation University Department of Radiology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom

Jonathan H. Gillard

Affiliation University Department of Radiology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom

Johan H. C. Reiber

Affiliation Division of Image Processing, Department of Radiology, Leiden University Medical Center, Leiden, The Netherlands

Rob J. van der Geest

rvdgeest@lumc.nl

Affiliation Division of Image Processing, Department of Radiology, Leiden University Medical Center, Leiden, The Netherlands

Competing Interests

The authors have read the journal's policy and have the following conflicts: JHCR is the CEO of Medis medical imaging systems bv. RJVDG received a consultancy fee from Medis medical imaging systems bv. AJP was supported by a Biomedical Research Centre grant. This does not alter their adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: RVTK AJP VEY RJVDG. Performed the experiments: RVTK AJP VEY. Analyzed the data: RVTK AJP VEY. Contributed reagents/materials/analysis tools: RVTK AJP VEY RJVDG. Wrote the manuscript: RVTK AJP VEY JHG JHCR RJVDG.