About the Authors
- Yaiza Diaz-de-Durana
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Contributed equally to this work with: Yaiza Diaz-de-Durana, Janet Lau
Affiliation Genetics Department, Genomics Institute of the Novartis Research Foundation, San Diego, California, United States of America
- Janet Lau
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Contributed equally to this work with: Yaiza Diaz-de-Durana, Janet Lau
Current address: Genentech, South San Francisco, California, United States of America
Affiliation Genetics Department, Genomics Institute of the Novartis Research Foundation, San Diego, California, United States of America
- Deborah Knee
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Affiliation Biotherapeutics Department, Genomics Institute of the Novartis Research Foundation, San Diego, California, United States of America
- Christophe Filippi
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Affiliation Genetics Department, Genomics Institute of the Novartis Research Foundation, San Diego, California, United States of America
- Marco Londei
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Current address: Bristol-Myers Squibb, Princeton, New Jersey, United States of America
Affiliation Translational Medicine, Novartis Institutes of Biomedical Research, San Diego, California, United States of America
- Peter McNamara
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Affiliation Pharmacology Department, Genomics Institute of the Novartis Research Foundation, San Diego, California, United States of America
- Marc Nasoff
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Affiliation Biotherapeutics Department, Genomics Institute of the Novartis Research Foundation, San Diego, California, United States of America
- Michael DiDonato
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Affiliation Structural Biology Department, Genomics Institute of the Novartis Research Foundation, San Diego, California, United States of America
- Richard Glynne
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* E-mail: rglynne@gnf.org
Affiliation Genetics Department, Genomics Institute of the Novartis Research Foundation, San Diego, California, United States of America
- Ann E. Herman
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Current address: Genentech, South San Francisco, California, United States of America
Affiliation Genetics Department, Genomics Institute of the Novartis Research Foundation, San Diego, California, United States of America
Competing Interests
The authors declare that they were all employees of the Genomics Institute of the Novartis Research Foundation or Novartis Institutes of Biomedical Research, and owned stock in Novartis (except YD and JL), at the time this work was completed. This does not alter their adherance to all PLOS ONE policies on sharing data and materials.
Author Contributions
Conceived and designed the experiments: YD JL AEH. Performed the experiments: YD JL. Analyzed the data: YD JL AEH. Wrote the manuscript: JL AEH YD RG CF. Pharmacology support: PM. Protein sciences support: MD. Biotherapeutics support: DK MN. Translational sciences support: ML.