About the Authors
- Winnie W. Pong
-
Affiliation Department of Neurology, Washington University School of Medicine, St. Louis, Missouri, United States of America
- Jason Walker
-
Affiliation The Genome Institute, Washington University School of Medicine, St. Louis, Missouri, United States of America
- Todd Wylie
-
Affiliation The Genome Institute, Washington University School of Medicine, St. Louis, Missouri, United States of America
- Vincent Magrini
-
Affiliation The Genome Institute, Washington University School of Medicine, St. Louis, Missouri, United States of America
- Jingqin Luo
-
Affiliation Division of Biostatistics, Washington University School of Medicine, St. Louis, Missouri, United States of America
- Ryan J. Emnett
-
Affiliation Department of Neurology, Washington University School of Medicine, St. Louis, Missouri, United States of America
- Jaebok Choi
-
Affiliation Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri, United States of America
- Matthew L. Cooper
-
Affiliation Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri, United States of America
- Malachi Griffith
-
Affiliation The Genome Institute, Washington University School of Medicine, St. Louis, Missouri, United States of America
- Obi L. Griffith
-
Affiliation The Genome Institute, Washington University School of Medicine, St. Louis, Missouri, United States of America
- Joshua B. Rubin
-
Affiliation Department of Pediatrics, Division of Pediatric Hematology/Oncology, Washington University School of Medicine, St. Louis, Missouri, United States of America
- Gregory N. Fuller
-
Affiliation Department of Pathology, MD Anderson Cancer Center, Houston, Texas, United States of America
- David Piwnica-Worms
-
Affiliation BRIGHT Institute and Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, Missouri, United States of America
- Xi Feng
-
Affiliation Department of Stem Cell Biology and Regeneration, Cleveland Clinic Foundation, Cleveland, Ohio, United States of America
- Dolores Hambardzumyan
-
Affiliation Department of Stem Cell Biology and Regeneration, Cleveland Clinic Foundation, Cleveland, Ohio, United States of America
- John F. DiPersio
-
Affiliation Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri, United States of America
- Elaine R. Mardis
-
Affiliation The Genome Institute, Washington University School of Medicine, St. Louis, Missouri, United States of America
- David H. Gutmann
-
* E-mail: gutmannd@neuro.wustl.edu
Affiliation Department of Neurology, Washington University School of Medicine, St. Louis, Missouri, United States of America
Competing Interests
The authors have read the journal's policy and have the following potential conflicts; there are no direct conflicts of interest. Dr. Pong reports grants from the W. M. Keck Foundation during the conduct of the study. Dr. Feng reports personal fees from National Cancer Institute and Cleveland Clinic, and non-financial support from University of Michigan outside the submitted work. Dr. Mardis reports personal fees from Pacific Biosciences Inc and from Illumina Inc, and other from Life Technologies, outside the submitted work. Dr. Gutmann reports grants from National Cancer Institute and from National Institutes of Health during the conduct of the study; personal fees from Biomarin, outside the submitted work; In addition, Dr. Gutmann has Neurofibromatosis type 1 patents. None of these organizations were involved in the study design; collection, analysis and interpretation of data; writing of the paper; and/or decision to submit for publication. This does not alter their adherence to all the PLOS ONE policies on sharing data and materials.
Author Contributions
Conceived and designed the experiments: WWP ERM DHG. Performed the experiments: WWP RJE JC MLC XF. Analyzed the data: WWP JW TW VM JL RJE JC MLC MG OLG. Contributed reagents/materials/analysis tools: VM GNF DH JFD ERM DHG. Wrote the manuscript: WWP DHG. Jointly supervised research: WWP VM ERM DHG. Contributed to experimental design: JW TW VM JC JBR DP-W DH. Contributed to the preparation of the manuscript: WWP JW TW VM MG OLG. Edited and approved the manuscript: DHG WWP TW VM JL RJE JC MLC MG OLG JBR GNF DP-W XF DH JFP ERM.