About the Authors
- Sylvaine You
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Affiliations Université Paris Descartes, Sorbonne Paris Cité, Paris, France, Institut National de la Santé et de la Recherche Médicale, Unité 1013, Paris, France
- Luca Piali
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Affiliation Actelion Pharmaceuticals Ltd, Allschwil, Switzerland
- Chantal Kuhn
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Affiliations Université Paris Descartes, Sorbonne Paris Cité, Paris, France, Institut National de la Santé et de la Recherche Médicale, Unité 1013, Paris, France
- Beat Steiner
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Affiliation Actelion Pharmaceuticals Ltd, Allschwil, Switzerland
- Virginia Sauvaget
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Affiliations Université Paris Descartes, Sorbonne Paris Cité, Paris, France, Institut National de la Santé et de la Recherche Médicale, Unité 1013, Paris, France
- Fabrice Valette
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Affiliations Université Paris Descartes, Sorbonne Paris Cité, Paris, France, Institut National de la Santé et de la Recherche Médicale, Unité 1013, Paris, France
- Martine Clozel
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Affiliation Actelion Pharmaceuticals Ltd, Allschwil, Switzerland
- Jean-François Bach
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Affiliations Université Paris Descartes, Sorbonne Paris Cité, Paris, France, Institut National de la Santé et de la Recherche Médicale, Unité 1013, Paris, France
- Lucienne Chatenoud
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* E-mail: lucienne.chatenoud@inserm.fr
Affiliations Université Paris Descartes, Sorbonne Paris Cité, Paris, France, Institut National de la Santé et de la Recherche Médicale, Unité 1013, Paris, France
Competing Interests
The authors have read the journal’s policy and have the following conflicts. M. Clozel is one of the founders of Actelion Pharmaceuticals Ltd, senior vice-president, chief scientific officer, head of pharmacology and preclinical development, and member of the extended Actelion executive committee. L. Piali and B. Steiner are full-time employees of Actelion Pharmaceuticals Ltd. All other authors declare that there is no duality of interest associated with this manuscript. This does not alter the authors’ adherence to all the PLOS ONE policies on sharing data and materials.
Author Contributions
Conceived and designed the experiments: SY LC JFB LP. Performed the experiments: SY CK VS FV. Analyzed the data: SY CK LC. Contributed reagents/materials/analysis tools: LC LP BS MC. Wrote the paper: SY LC LP MC.