About the Authors

Tamara Antonio

Affiliations Department of Psychiatry, New York University School of Medicine, New York, New York, United States of America, Department of Biochemistry and Molecular Pharmacology, New York University School of Medicine, New York, New York, United States of America

Steven R. Childers

Affiliation Department of Physiology and Pharmacology, Wake Forest School of Medicine, Winston-Salem, North Carolina, United States of America

Richard B. Rothman

Affiliation Translational Pharmacology Research Section, National Institute on Drug Abuse Intramural Research Program, Baltimore, Maryland, United States of America

Christina M. Dersch

Affiliation Translational Pharmacology Research Section, National Institute on Drug Abuse Intramural Research Program, Baltimore, Maryland, United States of America

Christine King

Affiliations Department of Psychiatry, New York University School of Medicine, New York, New York, United States of America, Department of Biochemistry and Molecular Pharmacology, New York University School of Medicine, New York, New York, United States of America

Martin Kuehne

Affiliation Department of Chemistry, University of Vermont, Burlington, Vermont, United States of America

William G. Bornmann

Affiliation Department of Experimental Therapeutics, University of Texas M. D. Anderson Cancer Center, Houston, Texas, United States of America

Amy J. Eshleman

Affiliation Research Service, VA Medical Center, and Departments of Psychiatry and Behavioral Neuroscience, Oregon Health and Science University, Portland, Oregon, United States of America

Aaron Janowsky

Affiliation Research Service, VA Medical Center, and Departments of Psychiatry and Behavioral Neuroscience, Oregon Health and Science University, Portland, Oregon, United States of America

Eric R. Simon

Affiliations Department of Psychiatry, New York University School of Medicine, New York, New York, United States of America, Department of Biochemistry and Molecular Pharmacology, New York University School of Medicine, New York, New York, United States of America

Maarten E. A. Reith

Affiliations Department of Psychiatry, New York University School of Medicine, New York, New York, United States of America, Department of Biochemistry and Molecular Pharmacology, New York University School of Medicine, New York, New York, United States of America

Kenneth Alper

Kenneth.Alper@nyumc.org

Affiliations Department of Psychiatry, New York University School of Medicine, New York, New York, United States of America, Department of Neurology, New York University School of Medicine, New York, New York, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: KA MEAR TA ERS AJ RBR SRC. Performed the experiments: TA SRC RBR CMD CK MK AJE MEAR. Analyzed the data: MEAR TA SRC RBR CMD WGB AJE AJ. Contributed reagents/materials/analysis tools: MEAR SRC RBR MK WGB AJ. Wrote the manuscript: KA MEAR TA ERS AJ MK RBR SRC.