About the Authors

Romain Dissard

Affiliations Institut National de la Santé et de la Recherche Médicale (INSERM), U1048, Institut of Cardiovascular and Metabolic Disease, Toulouse, France, Université Toulouse III Paul-Sabatier, Toulouse, France

Julie Klein

Affiliation Plateau de Protéomique des Liquides Biologiques, Institut of Cardiovascular and Metabolic Disease, Toulouse, France

Cécile Caubet

Affiliations Institut National de la Santé et de la Recherche Médicale (INSERM), U1048, Institut of Cardiovascular and Metabolic Disease, Toulouse, France, Université Toulouse III Paul-Sabatier, Toulouse, France

Benjamin Breuil

Affiliations Institut National de la Santé et de la Recherche Médicale (INSERM), U1048, Institut of Cardiovascular and Metabolic Disease, Toulouse, France, Plateau de Protéomique des Liquides Biologiques, Institut of Cardiovascular and Metabolic Disease, Toulouse, France

Justyna Siwy

Affiliations Mosaiques Diagnostics GmbH, Hannover, Germany, Charite-Universitatsmedizin Berlin, Berlin, Germany

Janosch Hoffman

Affiliation Mosaiques Diagnostics GmbH, Hannover, Germany

Laurent Sicard

Affiliations Institut National de la Santé et de la Recherche Médicale (INSERM), U1048, Institut of Cardiovascular and Metabolic Disease, Toulouse, France, Université Toulouse III Paul-Sabatier, Toulouse, France

Laure Ducassé

Affiliations Institut National de la Santé et de la Recherche Médicale (INSERM), U1048, Institut of Cardiovascular and Metabolic Disease, Toulouse, France, Université Toulouse III Paul-Sabatier, Toulouse, France

Simon Rascalou

Affiliations Institut National de la Santé et de la Recherche Médicale (INSERM), U1048, Institut of Cardiovascular and Metabolic Disease, Toulouse, France, Université Toulouse III Paul-Sabatier, Toulouse, France

Bruno Payre

Affiliation Centre de Microscopie Electronique Appliquée à la Biologie, Toulouse, France

Marie Buléon

Affiliations Institut National de la Santé et de la Recherche Médicale (INSERM), U1048, Institut of Cardiovascular and Metabolic Disease, Toulouse, France, Université Toulouse III Paul-Sabatier, Toulouse, France

William Mullen

Affiliation Department of Proteomics and Systems Medicine, BHF Glasgow Cardiovascular Research Centre, Institute of Cardiovascular and Medical Sciences, College of Medical Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom

Harald Mischak

Affiliations Mosaiques Diagnostics GmbH, Hannover, Germany, Department of Proteomics and Systems Medicine, BHF Glasgow Cardiovascular Research Centre, Institute of Cardiovascular and Medical Sciences, College of Medical Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom

Ivan Tack

Affiliations Institut National de la Santé et de la Recherche Médicale (INSERM), U1048, Institut of Cardiovascular and Metabolic Disease, Toulouse, France, Université Toulouse III Paul-Sabatier, Toulouse, France

Jean-Loup Bascands

Affiliations Institut National de la Santé et de la Recherche Médicale (INSERM), U1048, Institut of Cardiovascular and Metabolic Disease, Toulouse, France, Université Toulouse III Paul-Sabatier, Toulouse, France

Bénédicte Buffin-Meyer

Affiliations Institut National de la Santé et de la Recherche Médicale (INSERM), U1048, Institut of Cardiovascular and Metabolic Disease, Toulouse, France, Université Toulouse III Paul-Sabatier, Toulouse, France

Joost P. Schanstra

joost-peter.schanstra@inserm.fr

Affiliations Institut National de la Santé et de la Recherche Médicale (INSERM), U1048, Institut of Cardiovascular and Metabolic Disease, Toulouse, France, Université Toulouse III Paul-Sabatier, Toulouse, France

Competing Interests

Harald Mischak is the founder and co-owner of Mosaiques Diagnostics, who developed the CE-MS technology. Justyna Siwy, Julie Klein and Janosch Hoffman are employed by Mosaiques. This does not alter the authors’ adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: RD JPS JLB BBM. Performed the experiments: RD LD BB SR LS MB BP. Analyzed the data: RD JK CC JS JH WM. Contributed reagents/materials/analysis tools: RD HM IT. Wrote the manuscript: RD JPS JLB BBM CC HM IT JK.