About the Authors

Taketo Wakai

Affiliation Microbiology and Fermentation Laboratory, Calpis Co., Ltd., Sagamihara-shi, Kanagawa, Japan

Naoyuki Yamamoto

naoyuki.yamamoto@calpis.co.jp

Affiliation Research and Development Planning Department, Calpis Co., Ltd., Sagamihara-shi, Kanagawa, Japan

Competing Interests

The two authors were employed by a commercial company (CALPIS Co., Ltd.). This does not alter the authors’ adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: NY TW. Performed the experiments: TW. Analyzed the data: NY TW. Contributed reagents/materials/analysis tools: TW. Wrote the paper: NY TW.