About the Authors

Cristiana Castaldo

Affiliation Pharmacology Department, Siena Biotech, Siena, Italy

Silvia Ciambellotti

Affiliation Magnetic Resonance Center (CERM), University of Florence, Sesto Fiorentino, Florence, Italy

Raquel de Pablo-Latorre

Affiliation Magnetic Resonance Center (CERM), University of Florence, Sesto Fiorentino, Florence, Italy

Daniela Lalli

Affiliation Department of Chemistry, University of Florence, Sesto Fiorentino, Florence, Italy

Valentina Porcari

Affiliation Pharmacology Department, Siena Biotech, Siena, Italy

Paola Turano

turano@cerm.unifi.it

Affiliations Magnetic Resonance Center (CERM), University of Florence, Sesto Fiorentino, Florence, Italy, Department of Chemistry, University of Florence, Sesto Fiorentino, Florence, Italy

Competing Interests

The authors have read the journal’s policy and have the following potential conflicts: Cristiana Castaldo and Valentina Porcari are employees of the drug discovery Company Siena Biotech. Siena Biotech was not directly involved in the study design, analysis, or writing of the paper, nor in the decision to submit the manuscript for publication. There are no patents, products in development or marketed products to declare. This does not alter the authors’ adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: DL RDP-L PT. Performed the experiments: CC SC RDP-L VP. Analyzed the data: DL CC VP. Contributed reagents/materials/analysis tools: SC RDP-L. Wrote the paper: RDP-L DL PT.