About the Authors

Jun Feng

Affiliation State Key Laboratory of Microbial Metabolism and School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, China

Jun Wu

Affiliation State Key Laboratory of Microbial Metabolism and School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, China

Nan Dai

Affiliation New England Biolabs, Inc., Research Department, Ipswich, Massachusetts, United States of America

Shuangjun Lin

Affiliation State Key Laboratory of Microbial Metabolism and School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, China

H. Howard Xu

Affiliation Department of Biological Sciences, California State University Los Angeles, Los Angeles, California, United States of America

Zixin Deng

Affiliation State Key Laboratory of Microbial Metabolism and School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, China

Xinyi He

xyhe@sjtu.edu.cn

Affiliation State Key Laboratory of Microbial Metabolism and School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, China

Competing Interests

Co-author Nan Dai is employed by New England Biolabs, Inc. There are no patents, products in development or marketed products to declare. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: JF XH. Performed the experiments: JF. Analyzed the data: JF SL HHX XH. Contributed reagents/materials/analysis tools: JW ZD. Wrote the paper: JF ND HHX XH.