About the Authors
- Megan L. Grove
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* E-mail: Megan.L.Grove@uth.tmc.edu
Affiliation School of Public Health, Human Genetics Center, The University of Texas Health Science Center at Houston, Houston, Texas, United States of America
- Bing Yu
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Affiliation School of Public Health, Human Genetics Center, The University of Texas Health Science Center at Houston, Houston, Texas, United States of America
- Barbara J. Cochran
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Affiliation School of Public Health, Human Genetics Center, The University of Texas Health Science Center at Houston, Houston, Texas, United States of America
- Talin Haritunians
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Affiliation Medical Genetics Institute, Cedars-Sinai Medical Center, Los Angeles, California, United States of America
- Joshua C. Bis
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Affiliation Cardiovascular Health Research Unit, University of Washington, Seattle, Washington, United States of America
- Kent D. Taylor
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Affiliation Medical Genetics Institute, Cedars-Sinai Medical Center, Los Angeles, California, United States of America
- Mark Hansen
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Affiliation Illumina, Inc., San Diego, California, United States of America
- Ingrid B. Borecki
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Affiliation Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, Missouri, United States of America
- L. Adrienne Cupples
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Affiliations Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, United States of America, Framingham Heart Study of the National, Heart, Lung, and Blood Institute, Framingham, Massachusetts, United States of America
- Myriam Fornage
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Affiliation Institute of Molecular Medicine, Center for Human Genetics, The University of Texas Health Science Center at Houston, Houston, Texas, United States of America
- Vilmundur Gudnason
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Affiliations Icelandic Heart Association, Research Institute, Kopavogur, Iceland, Faculty of Medicine, University of Iceland, Reykjavík, Iceland
- Tamara B. Harris
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Affiliation Laboratory of Population Science, National Institute on Aging, Bethesda, Maryland, United States of America
- Sekar Kathiresan
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Affiliations Center for Human Genetic Research and Cardiovascular Research Center, Massachusetts General Hospital, Boston, Massachusetts, United States of America, Harvard Medical School, Boston, Massachusetts, United States of America, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, United States of America
- Robert Kraaij
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Affiliation Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands
- Lenore J. Launer
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Affiliation Laboratory of Population Science, National Institute on Aging, Bethesda, Maryland, United States of America
- Daniel Levy
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Affiliation Framingham Heart Study of the National, Heart, Lung, and Blood Institute, Framingham, Massachusetts, United States of America
- Yongmei Liu
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Affiliation Department of Epidemiology and Prevention, Wake Forest University School of Medicine, Winston-Salem, North Carolina, United States of America
- Thomas Mosley
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Affiliation Department of Medicine, University of Mississippi Medical Center, Jackson, Mississippi, United States of America
- Gina M. Peloso
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Affiliations Center for Human Genetic Research and Cardiovascular Research Center, Massachusetts General Hospital, Boston, Massachusetts, United States of America, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, United States of America
- Bruce M. Psaty
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Affiliations Cardiovascular Health Research Unit, University of Washington, Seattle, Washington, United States of America, Department of Epidemiology, University of Washington, Seattle, Washington, United States of America, Department of Medicine, University of Washington, Seattle, Washington, United States of America, Department of Health Services, University of Washington, Seattle, Washington, United States of America, Group Health Research Institute, Seattle, Washington, United States of America
- Stephen S. Rich
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Affiliation Center for Public Health Genomics, University of Virginia, Charlottesville, Virginia, United States of America
- Fernando Rivadeneira
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Affiliations Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands, ErasmusAGE and Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands, Netherlands Consortium for Healthy Aging, Netherlands Genomics Initiative, Leiden, The Netherlands
- David S. Siscovick
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Affiliation Cardiovascular Health Research Unit, University of Washington, Seattle, Washington, United States of America
- Albert V. Smith
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Affiliations Icelandic Heart Association, Research Institute, Kopavogur, Iceland, Faculty of Medicine, University of Iceland, Reykjavík, Iceland
- Andre Uitterlinden
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Affiliations ErasmusAGE and Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands, Netherlands Consortium for Healthy Aging, Netherlands Genomics Initiative, Leiden, The Netherlands
- Cornelia M. van Duijn
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Affiliations ErasmusAGE and Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands, Netherlands Consortium for Healthy Aging, Netherlands Genomics Initiative, Leiden, The Netherlands
- James G. Wilson
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Affiliation Department of Physiology and Biophysics, University of Mississippi Medical Center, Jackson, Mississippi, United States of America
- Christopher J. O’Donnell
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Affiliations Framingham Heart Study of the National, Heart, Lung, and Blood Institute, Framingham, Massachusetts, United States of America, Cardiology Division, Massachusetts General Hospital, Boston, Massachusetts, United States of America
- Jerome I. Rotter
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Affiliation Medical Genetics Institute, Cedars-Sinai Medical Center, Los Angeles, California, United States of America
- Eric Boerwinkle
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Affiliations School of Public Health, Human Genetics Center, The University of Texas Health Science Center at Houston, Houston, Texas, United States of America, Human Genome Sequencing Center, Baylor College of Medicine, Houston, Texas, United States of America
Competing Interests
Mark Hansen is an employee of Illumina, Inc. This does not alter the authors’ adherence to all the PLOS ONE policies on sharing data and materials. All authors have declared that no competing interests exist.
Author Contributions
Conceived and designed the experiments: JCB KDT IBB LAC MF VG SK DL YL BMP SSR DSS AVS AU CMVD JGW CJO JIR EB. Performed the experiments: MLG BJC TH MH YL RK FR. Analyzed the data: MLG BY EB. Contributed reagents/materials/analysis tools: KDT IBB MF VG SK YL GMP BMP SSR DSS AVS AU CMVD JGW CJO JIR EB. Wrote the paper: MLG BY BJC TH JCB KDT MH IBB LAC MF VG TBH SK RK LJL DL YL TM GMP BMP SSR FR DSS AVS AU CMVD JGW CJO JIR EB.