About the Authors

Sae-Won Han

Contributed equally to this work with: Sae-Won Han, Hwang-Phill Kim

Affiliations Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea, Cancer Research Institute, Seoul National University College of Medicine, Seoul, Korea

Hwang-Phill Kim

Contributed equally to this work with: Sae-Won Han, Hwang-Phill Kim

Affiliation Cancer Research Institute, Seoul National University College of Medicine, Seoul, Korea

Jong-Yeon Shin

Affiliations Genomic Medicine Institute, Medical Research Center, Seoul National University, Seoul, Korea, Psoma Therapeutics Inc., Seoul, Korea

Eun-Goo Jeong

Affiliation Cancer Research Institute, Seoul National University College of Medicine, Seoul, Korea

Won-Chul Lee

Affiliations Genomic Medicine Institute, Medical Research Center, Seoul National University, Seoul, Korea, Department of Biomedical Sciences, Seoul National University Graduate School, Seoul, Korea

Kyung-Hun Lee

Affiliation Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea

Jae-Kyung Won

Affiliation Department of Pathology, Seoul National University Hospital, Seoul, Korea

Tae-Yong Kim

Affiliation Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea

Do-Youn Oh

Affiliations Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea, Cancer Research Institute, Seoul National University College of Medicine, Seoul, Korea

Seock-Ah Im

Affiliations Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea, Cancer Research Institute, Seoul National University College of Medicine, Seoul, Korea

Yung-Jue Bang

Affiliations Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea, Cancer Research Institute, Seoul National University College of Medicine, Seoul, Korea

Seung-Yong Jeong

Affiliation Department of Surgery, Seoul National University Hospital, Seoul, Korea

Kyu Joo Park

Affiliation Department of Surgery, Seoul National University Hospital, Seoul, Korea

Jae-Gahb Park

Affiliation Department of Surgery, Seoul National University Hospital, Seoul, Korea

Gyeong Hoon Kang

Affiliation Department of Pathology, Seoul National University Hospital, Seoul, Korea

Jeong-Sun Seo

Affiliations Genomic Medicine Institute, Medical Research Center, Seoul National University, Seoul, Korea, Department of Biomedical Sciences, Seoul National University Graduate School, Seoul, Korea, Department of Biochemistry, Seoul National University College of Medicine, Seoul, Korea, Macrogen Inc., Seoul, Korea

Jong-Il Kim

Affiliations Genomic Medicine Institute, Medical Research Center, Seoul National University, Seoul, Korea, Psoma Therapeutics Inc., Seoul, Korea, Department of Biomedical Sciences, Seoul National University Graduate School, Seoul, Korea, Department of Biochemistry, Seoul National University College of Medicine, Seoul, Korea

Tae-You Kim

kimty@snu.ac.kr

Affiliations Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea, Cancer Research Institute, Seoul National University College of Medicine, Seoul, Korea, Department of Biomedical Sciences, Seoul National University Graduate School, Seoul, Korea, Department of Molecular Medicine & Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology, Seoul National University, Seoul, Korea

Competing Interests

The authors wish to declare that Jong-Yeon Shin and Jong-Il Kim are consultants for Psoma Therapeutics and Jeong-Sun Seo is a consultant for Macrogen. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: SWH JIK TYK. Performed the experiments: HPK JYS EGJ WCL. Analyzed the data: SWH HPK JYS EGJ WCL KHL JKW. Contributed reagents/materials/analysis tools: TYK DYO SAI YJB SYJ KJP JGP GHK JSS. Wrote the paper: SWH HPK JYS JIK TYK.