About the Authors

Anu Kantele

Contributed equally to this work with: Anu Kantele, Sari H. Pakkanen

anu.kantele@hus.fi

Affiliations Department of Medicine, Division of Infectious Diseases, Helsinki University Central Hospital, Helsinki, Finland, Department of Bacteriology and Immunology, Haartman Institute, University of Helsinki, Helsinki, Finland, Institute of Clinical Medicine, Department of Medicine, University of Helsinki, Helsinki, Finland

Sari H. Pakkanen

Contributed equally to this work with: Anu Kantele, Sari H. Pakkanen

Affiliations Department of Medicine, Division of Infectious Diseases, Helsinki University Central Hospital, Helsinki, Finland, Department of Bacteriology and Immunology, Haartman Institute, University of Helsinki, Helsinki, Finland

Riitta Karttunen

Affiliation Division of Clinical Microbiology, Department of Virology and Immunology, Helsinki University Hospital, Helsinki, Finland

Jussi M. Kantele

Affiliation Department of Medical Microbiology and Immunology, University of Turku, Turku, Finland

Competing Interests

AK has participated as a member in advisory boards of Pfizer, GlaxoSmithKline, and Novartis and received honoraria from these. She has acted as a consultant to Crucell on vaccination immunology and been reimbursed for giving lectures by Crucell, GSK, and Bayer. This work was supported by Crucell Switzerland AG. This does not alter the authors' adherence to all PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: AK SP RK JK. Performed the experiments: SP. Analyzed the data: AK JK SP. Contributed reagents/materials/analysis tools: AK RK. Wrote the paper: AK JK SP.