About the Authors

Chung-Feng Huang

Affiliations Institute of Clinical Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan, Hepatobiliary Division, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan, Department of Occupational Medicine, Kaohsiung Municipal Ta-Tung Hospital, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan

Chia-Yen Dai

fish6069@gmail.com

Affiliations Hepatobiliary Division, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan, Department of Preventive Medicine, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan, Faculty of Internal Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan

Ming-Lun Yeh

Affiliation Hepatobiliary Division, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan

Jee-Fu Huang

Affiliations Hepatobiliary Division, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan, Faculty of Internal Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan, Department of Internal Medicine, Kaohsiung Municipal Hsiao-Kang Hospital, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan

Ching-I Huang

Affiliation Department of Internal Medicine, Kaohsiung Municipal Ta-Tung Hospital, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan

Ming-Yen Hsieh

Affiliation Department of Internal Medicine, Kaohsiung Municipal Ta-Tung Hospital, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan

Zu-Yau Lin

Affiliations Hepatobiliary Division, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan, Faculty of Internal Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan

Shinn-Cherng Chen

Affiliations Hepatobiliary Division, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan, Faculty of Internal Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan

Liang-Yen Wang

Affiliations Hepatobiliary Division, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan, Faculty of Internal Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan

Suh-Hang Hank Juo

Affiliation Department of Medical Genetics, Kaohsiung Medical University, Kaohsiung, Taiwan

Wan-Long Chuang

Affiliations Hepatobiliary Division, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan, Faculty of Internal Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan

Yi-Ching Lin

Affiliations Institute of Clinical Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan, Department of Laboratory Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan

Ming-Lung Yu

Affiliations Hepatobiliary Division, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan, Faculty of Internal Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan

Competing Interests

The authors have read the journal's policy and have the following conflicts: co-author Ming-Lung Yu is the member of advisory board of Merck Sharp & Dohme (MSD), Roche and Abbott and on the PLOS editorial board. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Acquisition of data: CFH CIH MLY MYH JFH CYD ZYL SCC LYW. Approval of the final version of the manuscript: MLY CYD. Conceived and designed the experiments: MLY CFH WLC CYD. Analyzed the data: CFH JFH CYD WLC MLY. Contributed reagents/materials/analysis tools: SHJ YCL. Wrote the paper: CFH MLY JFH WLC CYD.