About the Authors

Matthew Schwede

Affiliation Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America

Dimitrios Spentzos

Affiliation Division of Hematology/Oncology, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States of America

Stefan Bentink

Affiliations Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America, Exosome Diagnostics GmbH, Martinsried, Germany

Oliver Hofmann

Affiliation Biostatistics, Harvard School of Public Health, Boston, Massachusetts, United States of America

Benjamin Haibe-Kains

Affiliations Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America, Integrative Systems Biology, Institut de recherches cliniques de Montréal, Montreal, Quebec, Canada

David Harrington

Affiliations Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America, Biostatistics, Harvard School of Public Health, Boston, Massachusetts, United States of America

John Quackenbush

Affiliations Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America, Biostatistics, Harvard School of Public Health, Boston, Massachusetts, United States of America, Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America

Aedín C. Culhane

aedin@jimmy.harvard.edu

Affiliations Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America, Biostatistics, Harvard School of Public Health, Boston, Massachusetts, United States of America

Competing Interests

SB is an employee of Exosome Diagnostics GmbH; JQ is Exosome Diagnostics Scientific Advisory Board Member and has minimal stock options in the company. Neither this nor any other affiliations alters the authors’ adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: ACC MS DH. Performed the experiments: MS ACC. Analyzed the data: MS ACC SB. Contributed reagents/materials/analysis tools: OH SB BHK JQ. Wrote the paper: MS ACC DS JQ.