About the Authors

Charles F. Gilks

Contributed equally to this work with: Charles F. Gilks, A. Sarah Walker

Affiliation Department of Medicine, Imperial College, London, United Kingdom

A. Sarah Walker

Contributed equally to this work with: Charles F. Gilks, A. Sarah Walker

asw@ctu.mrc.ac.uk

Affiliation Medical Research Council Clinical Trials Unit, London, United Kingdom

Paula Munderi

Affiliation Medical Research Council/ Uganda Virus Research Institute Uganda Research Unit on AIDS, Entebbe, Uganda

Cissy Kityo

Affiliation Joint Clinical Research Centre, Kampala, Uganda

Andrew Reid

Affiliation Clinical Research Centre, University of Zimbabwe, Harare, Zimbabwe

Elly Katabira

Affiliation Infectious Diseases Institute, Mulago, Uganda

Ruth L. Goodall

Affiliation Medical Research Council Clinical Trials Unit, London, United Kingdom

Heiner Grosskurth

Affiliation Medical Research Council/ Uganda Virus Research Institute Uganda Research Unit on AIDS, Entebbe, Uganda

Peter Mugyenyi

Affiliation Joint Clinical Research Centre, Kampala, Uganda

James Hakim

Affiliation Clinical Research Centre, University of Zimbabwe, Harare, Zimbabwe

Diana M. Gibb

Affiliation Medical Research Council Clinical Trials Unit, London, United Kingdom

on behalf of the DART Virology Group and Trial Team

Competing Interests

Viiv Healthcare/GlaxoSmithKline, Gilead and Boehringer-Ingelheim donated first-line drugs for DART, and Abbott provided Kaletra/Aluvia as part of the second-line regimen for DART. There are no patents, products in development or marketed products to declare. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Contributed to interpretation, revised manuscript critically and approved final version: CFG ASW P. Munderi CK AR EK RLG HG P. Mugyenyi JH DMG. Conceived and designed the experiments: CFG ASW DMG. Performed the experiments: P. Munderi CK AR EK HG P. Mugyenyi JH CFG ASW RLG DMG. Analyzed the data: ASW. Wrote the paper: CFG ASW DMG.