About the Authors

Marion Mortamais

Affiliations Inserm, U1061, La Colombière Hospital, Montpellier, France, University of Montpellier 1, Montpellier, France

Christelle Reynes

Affiliations University of Montpellier 1, Montpellier, France, EA 2415, Faculté de Pharmacie, Montpellier, France

Adam M. Brickman

Affiliation Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University, College of Physicians and Surgeons, New York, New York, United States of America

Frank A. Provenzano

Affiliation Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University, College of Physicians and Surgeons, New York, New York, United States of America

Jordan Muraskin

Affiliation Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University, College of Physicians and Surgeons, New York, New York, United States of America

Florence Portet

Affiliations Inserm, U1061, La Colombière Hospital, Montpellier, France, Unité Transversale des Troubles Neurologiques du Sujet Âgé, CHU Caremeau, Centre Ruffi, Pôle de Gériatrie, CHU Nîmes, Nîmes, France, Montpellier University Hospital, University Department of Adult Psychiatry, La Colombière Hospital, CHU de Montpellier, Montpellier, France

Claudine Berr

Affiliations Inserm, U1061, La Colombière Hospital, Montpellier, France, University of Montpellier 1, Montpellier, France

Jacques Touchon

Affiliations Inserm, U1061, La Colombière Hospital, Montpellier, France, University of Montpellier 1, Montpellier, France

Alain Bonafé

Affiliations University of Montpellier 1, Montpellier, France, CHRU Montpellier, Montpellier, France

Emmanuelle le Bars

Affiliations University of Montpellier 1, Montpellier, France, CHRU Montpellier, Montpellier, France

Jerome J. Maller

Affiliation Monash Alfred Psychiatry Research Centre, The Alfred and Monash University Central Clinical School, Melbourne, Australia

Chantal Meslin

Affiliation Centre for Mental Health Research, Australian National University, Canberra, Australia

Robert Sabatier

Affiliations University of Montpellier 1, Montpellier, France, EA 2415, Faculté de Pharmacie, Montpellier, France

Karen Ritchie

Affiliations Inserm, U1061, La Colombière Hospital, Montpellier, France, University of Montpellier 1, Montpellier, France, Faculty of Medicine, Imperial College, London, United Kingdom

Sylvaine Artero

sylvaine.artero@inserm.fr

Affiliations Inserm, U1061, La Colombière Hospital, Montpellier, France, University of Montpellier 1, Montpellier, France

Competing Interests

The authors received funding from a commercial source (Novartis). This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: KR CB JT SA. Performed the experiments: AB ElB. Analyzed the data: MM SA CR RS. Contributed reagents/materials/analysis tools: J. Maller CM FP AMB FAP J. Muraskin. Wrote the paper: MM SA.