About the Authors

Shankar Varadarajan

Affiliation MRC Toxicology Unit, University of Leicester, Leicester, United Kingdom

Kayoko Tanaka

Contributed equally to this work with: Kayoko Tanaka, Joshua L. Smalley

Affiliation Department of Biochemistry, University of Leicester, Leicester, United Kingdom

Joshua L. Smalley

Contributed equally to this work with: Kayoko Tanaka, Joshua L. Smalley

Affiliation MRC Toxicology Unit, University of Leicester, Leicester, United Kingdom

Edward T. W. Bampton

Affiliation MRC Toxicology Unit, University of Leicester, Leicester, United Kingdom

Maurizio Pellecchia

Affiliation Sanford-Burnham Institute, La Jolla, California, United States of America

David Dinsdale

Affiliation MRC Toxicology Unit, University of Leicester, Leicester, United Kingdom

Gary B. Willars

Affiliation Department of Cell Physiology and Pharmacology, University of Leicester, Leicester, United Kingdom

Gerald M. Cohen

gmc2@le.ac.uk

Affiliations MRC Toxicology Unit, University of Leicester, Leicester, United Kingdom, Department of Biochemistry, University of Leicester, Leicester, United Kingdom

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: SV KT ETWB GBW GMC. Performed the experiments: SV KT JLS ETWB DD. Analyzed the data: SV KT JLS ETWB DD GBW GMC. Contributed reagents/materials/analysis tools: MP JLS DD. Wrote the paper: SV KT MP DD GBW GMC. Provided cells: CT. Provided technical assistance: JMW TS.