About the Authors
- Michael F. Hill
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Contributed equally to this work with: Michael F. Hill, Amish V. Patel
Affiliation Division of Cardiovascular Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America
- Amish V. Patel
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Contributed equally to this work with: Michael F. Hill, Amish V. Patel
Affiliation Division of Cardiovascular Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America
- Abigail Murphy
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Affiliation Division of Cardiovascular Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America
- Holly M. Smith
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Affiliation Division of Cardiovascular Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America
- Cristi L. Galindo
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Affiliation Division of Cardiovascular Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America
- Laura Pentassuglia
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Affiliation Division of Cardiovascular Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America
- Xuyang Peng
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Affiliation Division of Cardiovascular Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America
- Carrie G. Lenneman
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Current address: Division of Cardiovascular Medicine, University of Louisville School of Medicine, Louisville. Kentucky, United States of America
Affiliation Division of Cardiovascular Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America
- Oghenerukevwe Odiete
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Affiliation Division of Cardiovascular Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America
- David B. Friedman
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Affiliation Department of Biochemistry, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America
- Marvin W. Kronenberg
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Affiliation Division of Cardiovascular Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America
- Siyuen Zheng
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Affiliation Biomedical Informatics and Cancer Biology, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America
- Zhongming Zhao
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Affiliation Biomedical Informatics and Cancer Biology, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America
- Yanna Song
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Affiliation Department of Biostatistics, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America
- Frank E. Harrell Jr
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Affiliation Department of Biostatistics, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America
- Maya Srinivas
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Affiliation Acorda Therapeutics, Inc., Hawthorne, New York, United States of America
- Anindita Ganguly
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Affiliation Acorda Therapeutics, Inc., Hawthorne, New York, United States of America
- Jennifer Iaci
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Affiliation Acorda Therapeutics, Inc., Hawthorne, New York, United States of America
- Tom J. Parry
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Affiliation Acorda Therapeutics, Inc., Hawthorne, New York, United States of America
- Anthony O. Caggiano
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Affiliation Acorda Therapeutics, Inc., Hawthorne, New York, United States of America
- Douglas B. Sawyer
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* E-mail: douglas.b.sawyer@Vanderbilt.Edu
Affiliation Division of Cardiovascular Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America
Competing Interests
Douglas Sawyer has received research support from Acorda Therapeutics, Inc. that helped to fund parts of this study. Several authors as noted on the title page are employees of Acorda Therapeutics, Inc., a company that is developing GGF2 for the treatment of cardiovascular and neurodegenerative disease. The authors note that these competing interests do not alter their adherence to all the PLOS ONE policies on sharing data and materials, as detailed online in the guide for authors.
Author Contributions
Conceived and designed the experiments: MFH AVP AM HMS CLG LP XP CGL OO DBF MWK SZ ZZ YS FEH MS AG JI TJP AOC DBS. Performed the experiments: MFH AVP AM HMS CLG LP XP CGL OO DBF MWK SZ ZZ DBS. Analyzed the data: MFH AVP AM HMS CLG LP XP CGL OO DBF MWK SZ ZZ YS FEH MS AG JI TJP AOC DBS. Contributed reagents/materials/analysis tools: DBF SZ ZZ YS FEH MS AG JI TJP AOC. Wrote the paper: MFH AVP AM HMS CLG LP XP CGL OO DBF MWK SZ ZZ YS FEH MS AG JI TJP AOC DBS.