About the Authors

Saskia A. Overbeek

Affiliation Division of Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Faculty of Science, Utrecht University, Utrecht, The Netherlands

Saskia Braber

Affiliation Division of Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Faculty of Science, Utrecht University, Utrecht, The Netherlands

Pim J. Koelink

Affiliation Division of Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Faculty of Science, Utrecht University, Utrecht, The Netherlands

Paul A. J. Henricks

Affiliation Division of Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Faculty of Science, Utrecht University, Utrecht, The Netherlands

Esmaeil Mortaz

Affiliations Division of Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Faculty of Science, Utrecht University, Utrecht, The Netherlands, Chronic Respiratory Disease Research center, National Research Institute of Tuberculosis and lung disease (NRITLD), Masih Daneshvari Hospital, Shahid Beheshti University of Medical sciences, Tehran, Iran

Adele T. LoTam Loi

Affiliation Department of Respiratory Medicine, University Medical Center Utrecht, Utrecht, The Netherlands

Patricia L. Jackson

Affiliation Division of Pulmonary, Allergy and Critical Care Medicine and UAB Lung Health Center, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, United States of America

Johan Garssen

Affiliations Division of Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Faculty of Science, Utrecht University, Utrecht, The Netherlands, Danone Research – Centre for Specialised Nutrition, Wageningen, The Netherlands

Gerry T. M. Wagenaar

Affiliation Department of Pediatrics, Division of Neonatology, Leiden University Medical Center, Leiden, The Netherlands

Wim Timens

Affiliation Department of Pathology and Medical Biology, University Medical Center Groningen, Groningen, The Netherlands

Leo Koenderman

Affiliation Chronic Respiratory Disease Research center, National Research Institute of Tuberculosis and lung disease (NRITLD), Masih Daneshvari Hospital, Shahid Beheshti University of Medical sciences, Tehran, Iran

J. Edwin Blalock

Affiliation Department of Respiratory Medicine, University Medical Center Utrecht, Utrecht, The Netherlands

Aletta D. Kraneveld

Affiliation Division of Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Faculty of Science, Utrecht University, Utrecht, The Netherlands

Gert Folkerts

G.Folkerts@uu.nl

Affiliation Division of Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Faculty of Science, Utrecht University, Utrecht, The Netherlands

Competing Interests

JG is employed by a commercial company, Danone Research. However, this does not alter the authors’ adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: SAO PAJH JG ADK GF. Performed the experiments: SAO SB PJK PJ EM. Analyzed the data: SAO SB PJK PAJH GTMW ADK GF. Contributed reagents/materials/analysis tools: ATL WT LK JEB. Wrote the paper: SAO PAJH ADK GF.