About the Authors

Shaheen Akhtar

Affiliation Medical Research Council Prion Unit and Department of Neurodegenerative Disease, University College London Institute of Neurology, London, United Kingdom

Julia Grizenkova

Affiliation Medical Research Council Prion Unit and Department of Neurodegenerative Disease, University College London Institute of Neurology, London, United Kingdom

Adam Wenborn

Affiliation Medical Research Council Prion Unit and Department of Neurodegenerative Disease, University College London Institute of Neurology, London, United Kingdom

Holger Hummerich

Affiliation Medical Research Council Prion Unit and Department of Neurodegenerative Disease, University College London Institute of Neurology, London, United Kingdom

Mar Fernandez de Marco

Affiliation Medical Research Council Prion Unit and Department of Neurodegenerative Disease, University College London Institute of Neurology, London, United Kingdom

Sebastian Brandner

Affiliation Medical Research Council Prion Unit and Department of Neurodegenerative Disease, University College London Institute of Neurology, London, United Kingdom

John Collinge

Affiliation Medical Research Council Prion Unit and Department of Neurodegenerative Disease, University College London Institute of Neurology, London, United Kingdom

Sarah E. Lloyd

s.lloyd@prion.ucl.ac.uk

Affiliation Medical Research Council Prion Unit and Department of Neurodegenerative Disease, University College London Institute of Neurology, London, United Kingdom

Competing Interests

JC is a director and shareholder of D-Gen limited, an academic spin-out company in the field of prion diagnosis, decontamination and therapeutics. This does not alter the authors’ adherence to all the PLOS One policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: SL. Performed the experiments: SA JG AW MFdeM SL. Analyzed the data: SB HH SL. Wrote the paper: SL JC.