About the Authors

Dong Shi

Affiliations Department of Ophthalmology, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan, Department of Ophthalmology, the Fourth Affiliated Hospital, China Medical University, Shenyang, Liaoning, China

Tomoyo Funayama

Affiliation Department of Chemistry, Faculty of Education, Bunkyo University, Koshigaya, Saitama, Japan

Yukihiko Mashima

Affiliation Department of Ophthalmology, Keio University School of Medicine, Shinjuku-ku, Tokyo, Japan

Yoshimasa Takano

Affiliation Department of Ophthalmology, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan

Ai Shimizu

Affiliation Department of Ophthalmology, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan

Kotaro Yamamoto

Affiliation Department of Ophthalmology, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan

MinGe Mengkegale

Affiliation Department of Ophthalmology, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan

Akiko Miyazawa

Affiliation Department of Ophthalmology, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan

Noriko Yasuda

Affiliation Department of Ophthalmology, Tokyo Metropolitan Police Hospital, Tokyo, Japan

Takeo Fukuchi

Affiliation Division of Ophthalmology and Visual Science, Graduate School of Medical and Dental Sciences, Niigata University, Niigata, Japan

Haruki Abe

Affiliation Division of Ophthalmology and Visual Science, Graduate School of Medical and Dental Sciences, Niigata University, Niigata, Japan

Hidenao Ideta

Affiliation Ideta Eye Hospital, Kumamoto, Japan

Kohji Nishida

Affiliation Department of Ophthalmology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan

Toru Nakazawa

Affiliation Department of Ophthalmology, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan

Julia E. Richards

Affiliations Department of Ophthalmology and Visual Sciences, W. K. Kellogg Eye Center, University of Michigan, Ann Arbor, Michigan, United States of America, Department of Epidemiology, University of Michigan, Ann Arbor, Michigan, United States of America

Nobuo Fuse

fusen@oph.med.tohoku.ac.jp

Affiliations Department of Ophthalmology, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan, Department of Integrative Genomics, Tohoku Medical Megabank Organization, Sendai, Miyagi, Japan

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: T. Funayama YM KN NF. Performed the experiments: DS T. Funayama YT AS KY MM AM TN NF. Analyzed the data: DS T. Funayama YM JER NF. Contributed reagents/materials/analysis tools: T. Funayama YT AS NY T. Fukuchi HA HI TN. Wrote the paper: DS KY JER NF.