About the Authors

Joseph T. Glessner

Affiliation Center for Applied Genomics, The Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America

Albert Vernon Smith

Affiliations Icelandic Heart Association, Heart Preventive Clinic and Research Institute, Kopavogur, Iceland, University of Iceland, Reykjavik, Iceland

Saarene Panossian

Affiliation Center for Applied Genomics, The Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America

Cecilia E. Kim

Affiliation Center for Applied Genomics, The Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America

Nagahide Takahashi

Affiliation Laboratory of Molecular Neuropsychiatry, Department of Psychiatry, Mount Sinai School of Medicine, New York, New York, United States of America

Kelly A. Thomas

Affiliation Center for Applied Genomics, The Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America

Fengxiang Wang

Affiliation Center for Applied Genomics, The Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America

Kallyn Seidler

Affiliation Center for Applied Genomics, The Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America

Tamara B. Harris

Affiliation Laboratory of Epidemiology, Demography, and Biometry, National Institute on Aging, National Institutes of Health, Bethesda, Maryland, United States of America

Lenore J. Launer

Affiliation Laboratory of Epidemiology, Demography, and Biometry, National Institute on Aging, National Institutes of Health, Bethesda, Maryland, United States of America

Brendan Keating

Affiliation Center for Applied Genomics, The Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America

John Connolly

Affiliation Center for Applied Genomics, The Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America

Patrick M. A. Sleiman

Affiliation Center for Applied Genomics, The Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America

Joseph D. Buxbaum

Affiliation Laboratory of Molecular Neuropsychiatry, Department of Psychiatry, Mount Sinai School of Medicine, New York, New York, United States of America

Struan F. A. Grant

Affiliations Center for Applied Genomics, The Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America, Division of Genetics, The Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America, Department of Pediatrics, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, United States of America

Vilmundur Gudnason

Affiliations Icelandic Heart Association, Heart Preventive Clinic and Research Institute, Kopavogur, Iceland, University of Iceland, Reykjavik, Iceland

Hakon Hakonarson

hakonarson@chop.edu

Affiliations Center for Applied Genomics, The Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America, Division of Genetics, The Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America, Department of Pediatrics, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: HH VG TBH LJL JDB SFAG. Performed the experiments: CEK NT KAT KS. Analyzed the data: JTG AVS. Contributed reagents/materials/analysis tools: SP FW BK JC PMAS. Wrote the paper: JTG AVS VG HH.