About the Authors

Firdaus A. A. Mohamed Hoesein

Contributed equally to this work with: Firdaus A. A. Mohamed Hoesein, Els Wauters

fmohamedhoesein@gmail.com

Affiliation Division of Heart and Lungs, Department of Respiratory Medicine, University Medical Center, Utrecht, The Netherlands

Els Wauters

Contributed equally to this work with: Firdaus A. A. Mohamed Hoesein, Els Wauters

Affiliations Respiratory Division, University Hospital Gasthuisberg, KU Leuven, Leuven, Belgium, Vesalius Research Center, VIB, Leuven, Belgium, Vesalius Research Center, KU Leuven, Leuven, Belgium

Wim Janssens

Affiliation Respiratory Division, University Hospital Gasthuisberg, KU Leuven, Leuven, Belgium

Harry J. M. Groen

Affiliation Department of Pulmonology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands

Joanna Smolonska

Affiliation Department of Genetics, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands

Cisca Wijmenga

Affiliation Department of Genetics, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands

Dirkje S. Postma

Affiliation Department of Pulmonology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands

H. Marike Boezen

Affiliation Department of Epidemiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands

Pim A. De Jong

Affiliation Department of Radiology, University Medical Center, Utrecht, The Netherlands

Marc Decramer

Affiliation Respiratory Division, University Hospital Gasthuisberg, KU Leuven, Leuven, Belgium

Jan-Willem J. Lammers

Affiliation Division of Heart and Lungs, Department of Respiratory Medicine, University Medical Center, Utrecht, The Netherlands

Diether Lambrechts

Affiliations Vesalius Research Center, VIB, Leuven, Belgium, Vesalius Research Center, KU Leuven, Leuven, Belgium

Pieter Zanen

Affiliation Division of Heart and Lungs, Department of Respiratory Medicine, University Medical Center, Utrecht, The Netherlands

Competing Interests

DS Postma received funding for research from AstraZeneca, GSK, Nycomed. Travel to ERS or ATS has been partially funded by AstraZeneca, GSK, Chiesi, Nycomed. DS Postma has been consultant to AstraZeneca, Boehringer Ingelheim, Chiesi, GSK, Nycomed, TEVA. W Janssens has been consultant and received travel grants from Boehringer Ingelheim, Astra Zeneca, Nycomed. All the other authors state that they have no conflicts of interests. The above commercial funding was not for this specific study. This study was, however, funded by ‘Zorg Onderzoek Nederland-Medische Wetenschappen, KWF Kankerbestrijding, Stichting Centraal Fonds Reserves van Voormalig Vrijwillige Ziekenfondsverzekeringen, Siemens Germany, G. Ph. Verhagen Stichting, Rotterdam Oncologic Thoracic Steering Committee, Erasmus Trust Fund, Stichting tegen Kanker. There are no patents, products in development or marketed products to declare. This does not alter the authors’ adherence to all the PLOS ONE policies on sharing data and materials, as detailed online in the guide for authors.

Author Contributions

Conceived and designed the experiments: PZ WJ DL. Performed the experiments: JS EW. Analyzed the data: FMH EW PZ WJ DL. Contributed reagents/materials/analysis tools: JS. Wrote the paper: FMH EW PZ WJ DL HG CW DP MB PDJ MD JL.