About the Authors

Marcel Reichen

Affiliation Department of Biochemical Engineering, University College London, London, United Kingdom

Rhys J. Macown

Affiliation Department of Biochemical Engineering, University College London, London, United Kingdom

Nicolas Jaccard

Affiliations Department of Biochemical Engineering, University College London, London, United Kingdom, Centre for Mathematics and Physics in the Life Sciences and Experimental Biology, University College London, London, United Kingdom

Alexandre Super

Affiliation Department of Biochemical Engineering, University College London, London, United Kingdom

Ludmila Ruban

Affiliation Department of Biochemical Engineering, University College London, London, United Kingdom

Lewis D. Griffin

Affiliations Centre for Mathematics and Physics in the Life Sciences and Experimental Biology, University College London, London, United Kingdom, Department of Computer Science, University College London, London, United Kingdom

Farlan S. Veraitch

Affiliation Department of Biochemical Engineering, University College London, London, United Kingdom

Nicolas Szita

n.szita@ucl.ac.uk

Affiliation Department of Biochemical Engineering, University College London, London, United Kingdom

Competing Interests

A patent application has been filed by UCL Business, wholly-owned subsidiary of UCL (www.uclb.com). The application number is PCT/GB2009/002778. The authors Marcel Reichen and Nicolas Szita may become potential beneficiaries of that patent application in the future. There are no further products in development or marketed products to declare. This does not alter the authors’ adherence to all the PLOS ONE policies on sharing data and materials, as detailed online in the guide for authors.

Author Contributions

Conceived and designed the experiments: MR RJM NJ LR FSV NS. Performed the experiments: MR RJM NJ AS LR. Analyzed the data: MR RJM NJ LR LDG FSV NS. Contributed reagents/materials/analysis tools: MR RJM NJ. Wrote the paper: MR RJM NJ LDG FSV NS.