About the Authors

Dione T. Kobayashi

dkobayashi@smafoundation.org

Affiliation Spinal Muscular Atrophy Foundation, New York, New York, United States of America

Douglas Decker

Affiliation PharmOptima LLC, Portage, Michigan, United States of America

Phillip Zaworski

Affiliation PharmOptima LLC, Portage, Michigan, United States of America

Karen Klott

Affiliation Jasper Clinic, Kalamazoo, Michigan, United States of America

Julie McGonigal

Affiliation Jasper Clinic, Kalamazoo, Michigan, United States of America

Nabil Ghazal

Affiliation Jasper Clinic, Kalamazoo, Michigan, United States of America

Laurel Sly

Affiliation PharmOptima LLC, Portage, Michigan, United States of America

Brett Chung

Affiliation Spinal Muscular Atrophy Foundation, New York, New York, United States of America

James Vanderlugt

Affiliation Jasper Clinic, Kalamazoo, Michigan, United States of America

Karen S. Chen

Affiliation Spinal Muscular Atrophy Foundation, New York, New York, United States of America

Competing Interests

The authors have read the journal's policy and have the following conflicts: Authors DD, PZ and LS are employees of PharmOptima and KK, JM, NG, and JV are all employees of the Jasper Clinic. All are employed by for-profit companies and have received payments from the SMA Foundation to conduct the studies in this paper. This does not alter the authors' adherence to all PLOS ONE policies on data sharing and materials.

Author Contributions

Conceived and designed the experiments: DTK DD LS NG JV KSC. Performed the experiments: DD PZ LS KK JM. Analyzed the data: DTK BC DD LS. Contributed reagents/materials/analysis tools: KK NG JV. Wrote the paper: DTK DD LS.