About the Authors

Marisa Ojala

Affiliations Institute of Biomedical Technology, University of Tampere, Tampere, Finland, BioMediTech, University of Tampere, Tampere, Finland

Kristiina Rajala

Affiliations Institute of Biomedical Technology, University of Tampere, Tampere, Finland, BioMediTech, University of Tampere, Tampere, Finland

Mari Pekkanen-Mattila

Affiliations Institute of Biomedical Technology, University of Tampere, Tampere, Finland, BioMediTech, University of Tampere, Tampere, Finland

Marinka Miettinen

Affiliations Institute of Biomedical Technology, University of Tampere, Tampere, Finland, BioMediTech, University of Tampere, Tampere, Finland

Heini Huhtala

Affiliation School of Health Sciences, University of Tampere, Tampere, Finland

Katriina Aalto-Setälä

katriina.aalto-setala@uta.fi

Affiliations Institute of Biomedical Technology, University of Tampere, Tampere, Finland, BioMediTech, University of Tampere, Tampere, Finland, Heart Center, Tampere University Hospital, Tampere, Finland

Competing Interests

Author Katriina Aalto- Setälä is a PLOS ONE Editorial Board member. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: MO KR MPM KAS. Performed the experiments: MO KR MM. Analyzed the data: MO KR MPM HH. Wrote the paper: MO KR KAS.