About the Authors

Julie K. Hurt

Affiliation Department of Cell and Molecular Physiology, UNC Neuroscience Center, University of North Carolina at Chapel Hill, Chapel Hill, United States of America

Jennifer L. Coleman

Affiliation Department of Cell and Molecular Physiology, UNC Neuroscience Center, University of North Carolina at Chapel Hill, Chapel Hill, United States of America

Brendan J. Fitzpatrick

Affiliation Department of Cell and Molecular Physiology, UNC Neuroscience Center, University of North Carolina at Chapel Hill, Chapel Hill, United States of America

Bonnie Taylor-Blake

Affiliation Department of Cell and Molecular Physiology, UNC Neuroscience Center, University of North Carolina at Chapel Hill, Chapel Hill, United States of America

Arlene S. Bridges

Affiliation Department of Cell and Molecular Physiology, UNC Neuroscience Center, University of North Carolina at Chapel Hill, Chapel Hill, United States of America

Pirkko Vihko

Affiliation Department of Clinical Medicine, Division of Clinical Chemistry, HUSLAB, University of Helsinki, Helsinki, Finland

Mark J. Zylka

zylka@med.unc.edu

Affiliation Department of Cell and Molecular Physiology, UNC Neuroscience Center, University of North Carolina at Chapel Hill, Chapel Hill, United States of America

Competing Interests

The authors have read the journal's policy and have the following conflicts: M.J.Z. and P.V. are listed as inventors on a patent application (US Patent 2010/0266,569) that was licensed to a commercial entity for the purpose of developing PAP protein as a treatment for pain. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: JKH MJZ. Performed the experiments: JKH JLC BJF BTB ASB. Analyzed the data: JKH JLC BJF BTB ASB MJZ. Contributed reagents/materials/analysis tools: PV. Wrote the paper: JKH MJZ.