About the Authors

Yi Zhang

Affiliations The State Key Laboratory for Artificial Microstructures and Mesoscopic Physics, Center for Quantitative Biology, and School of Physics, Peking University, China, Department of Biochemistry and Biophysics and California Institute for Quantitative Biosciences, University of California San Francisco, San Francisco, California, United States of America

Chunxiong Luo

Affiliation The State Key Laboratory for Artificial Microstructures and Mesoscopic Physics, Center for Quantitative Biology, and School of Physics, Peking University, China

Ke Zou

Affiliations The State Key Laboratory for Artificial Microstructures and Mesoscopic Physics, Center for Quantitative Biology, and School of Physics, Peking University, China, Department of Biochemistry and Biophysics and California Institute for Quantitative Biosciences, University of California San Francisco, San Francisco, California, United States of America

Zhengwei Xie

Affiliation The State Key Laboratory for Artificial Microstructures and Mesoscopic Physics, Center for Quantitative Biology, and School of Physics, Peking University, China

Onn Brandman

Affiliation Department of Cellular and Molecular Pharmacology, University of California San Francisco, San Francisco, California, United States of America

Qi Ouyang

qi@pku.edu.cn (QO); haoli@genome.ucsf.edu (HL)

Affiliations The State Key Laboratory for Artificial Microstructures and Mesoscopic Physics, Center for Quantitative Biology, and School of Physics, Peking University, China, Department of Physics, Peking-Tsinghua Center for Life Sciences, Peking University, Beijing, China

Hao Li

qi@pku.edu.cn (QO); haoli@genome.ucsf.edu (HL)

Affiliation Department of Biochemistry and Biophysics and California Institute for Quantitative Biosciences, University of California San Francisco, San Francisco, California, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Constructed the strains used in the experiments: OB. Conceived and designed the experiments: YZ CL QO HL. Performed the experiments: YZ KZ. Analyzed the data: YZ HL. Contributed reagents/materials/analysis tools: ZX. Wrote the paper: YZ QO HL.