About the Authors
- Xiaomin Han
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Contributed equally to this work with: Xiaomin Han, Jing Zhang
Affiliation Institute of Medicinal Biotechnology, Peking Union Medical College & Chinese Academy of Medical Sciences, Beijing, People’s Republic of China
- Jing Zhang
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Contributed equally to this work with: Xiaomin Han, Jing Zhang
Affiliation Institute of Medicinal Biotechnology, Peking Union Medical College & Chinese Academy of Medical Sciences, Beijing, People’s Republic of China
- Liang Guo
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Affiliation Xinjiang Huashidan Pharmaceutical Co., Urumqi, People’s Republic of China
- Rihui Cao
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Affiliation Xinjiang Huashidan Pharmaceutical Co., Urumqi, People’s Republic of China
- Yongzhen Li
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Affiliation Institute of Medicinal Biotechnology, Peking Union Medical College & Chinese Academy of Medical Sciences, Beijing, People’s Republic of China
- Ni Li
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Affiliation Institute of Medicinal Biotechnology, Peking Union Medical College & Chinese Academy of Medical Sciences, Beijing, People’s Republic of China
- Qin Ma
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Affiliation Xinjiang Huashidan Pharmaceutical Co., Urumqi, People’s Republic of China
- Jialin Wu
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* E-mail: sisyimb@hotmail.com (SS); yanchang.wang@med.fsu.edu (YW); hsd_100@163.com (JW)
Affiliation Xinjiang Huashidan Pharmaceutical Co., Urumqi, People’s Republic of China
- Yanchang Wang
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* E-mail: sisyimb@hotmail.com (SS); yanchang.wang@med.fsu.edu (YW); hsd_100@163.com (JW)
Affiliation Department of Biomedical Sciences, College of Medicine, Florida State University, Tallahassee, Florida, United States of America
- Shuyi Si
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* E-mail: sisyimb@hotmail.com (SS); yanchang.wang@med.fsu.edu (YW); hsd_100@163.com (JW)
Affiliation Institute of Medicinal Biotechnology, Peking Union Medical College & Chinese Academy of Medical Sciences, Beijing, People’s Republic of China
Competing Interests
Liang Guo, Rihui Cao, Qin Ma and Jialin Wu are employed by the Xinjiang Huashidan Pharmaceutical Co. All the beta-carboline derivatives tested in this study were provided by Xinjiang Huashidan Pharmaceutical Co. Ltd. (The Patent information of Xinjiang Huashidan Pharmaceutical Co. Ltd as following: title: Beta-carboline derivatives and their application, Patent number: 201010108531.4 (China application number). There are no other patents, products in development or other marketed products to declare. This does not alter the authors’ adherence to all the PLOS ONE policies on sharing data and materials, as detailed online in the guide for authors.
Author Contributions
Conceived and designed the experiments: XMH JZ YCW SYS. Performed the experiments: XMH JZ YZL NL. Analyzed the data: XMH JZ YZL YCW SYS. Contributed reagents/materials/analysis tools: XMH JZ YZL NL LG RHC QM JLW YCW SYS. Wrote the paper: XMH JZ YZL YCW SYS. Contribution type: XMH JZ.