A Substitution in the Ligand Binding Domain of the Porcine Glucocorticoid Receptor Affects Activity of the Adrenal Gland

Eduard Murani; Henry Reyer; Siriluck Ponsuksili; Stephan Fritschka; Klaus Wimmers

doi:10.1371/journal.pone.0045518

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Peer-reviewed

Research Article

A Substitution in the Ligand Binding Domain of the Porcine Glucocorticoid Receptor Affects Activity of the Adrenal Gland

Eduard Murani ,

Contributed equally to this work with: Eduard Murani, Henry Reyer

Affiliation Research Unit Molecular Biology, Leibniz Institute for Farm Animal Biology (FBN), Dummerstorf, Germany
⨯
Henry Reyer ,

Contributed equally to this work with: Eduard Murani, Henry Reyer

Affiliation Research Unit Molecular Biology, Leibniz Institute for Farm Animal Biology (FBN), Dummerstorf, Germany
⨯
Siriluck Ponsuksili,

Affiliation Research Group Functional Genome Analysis, Leibniz Institute for Farm Animal Biology (FBN), Dummerstorf, Germany
⨯
Stephan Fritschka,

Affiliation Research Unit Molecular Biology, Leibniz Institute for Farm Animal Biology (FBN), Dummerstorf, Germany
⨯
Klaus Wimmers

* E-mail: wimmers@fbn-dummertorf.de

Affiliation Research Unit Molecular Biology, Leibniz Institute for Farm Animal Biology (FBN), Dummerstorf, Germany
⨯

A Substitution in the Ligand Binding Domain of the Porcine Glucocorticoid Receptor Affects Activity of the Adrenal Gland

Eduard Murani,
Henry Reyer,
Siriluck Ponsuksili,
Stephan Fritschka,
Klaus Wimmers

Published: September 18, 2012
https://doi.org/10.1371/journal.pone.0045518

About the Authors

Eduard Murani

Contributed equally to this work with: Eduard Murani, Henry Reyer

Affiliation Research Unit Molecular Biology, Leibniz Institute for Farm Animal Biology (FBN), Dummerstorf, Germany

Henry Reyer

Contributed equally to this work with: Eduard Murani, Henry Reyer

Affiliation Research Unit Molecular Biology, Leibniz Institute for Farm Animal Biology (FBN), Dummerstorf, Germany

Siriluck Ponsuksili

Affiliation Research Group Functional Genome Analysis, Leibniz Institute for Farm Animal Biology (FBN), Dummerstorf, Germany

Stephan Fritschka

Affiliation Research Unit Molecular Biology, Leibniz Institute for Farm Animal Biology (FBN), Dummerstorf, Germany

Klaus Wimmers

* E-mail: wimmers@fbn-dummertorf.de

Affiliation Research Unit Molecular Biology, Leibniz Institute for Farm Animal Biology (FBN), Dummerstorf, Germany

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: EM KW. Performed the experiments: HR SP SF. Analyzed the data: EM HR SP SF KW. Contributed reagents/materials/analysis tools: EM HR SP SF KW. Wrote the paper: EM.

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Single nucleotide polymorphisms
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Cortisol
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Haplotypes
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Genome-wide association studies
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Swine
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Adrenal glands
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Linkage disequilibrium
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Phenotypes
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